CRCGN010_HEPG2_24H:L19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfuric acid compound with 2-methyl-1,4-benzenediamine (1:1) 20.89 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

435 genes differentially expressed following the CRCGN010_HEPG2_24H:L19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TXNRD1 thioredoxin reductase 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 7.99074
SQOR sulfide quinone oxidoreductase 7.5605
RAP1GAP RAP1 GTPase activating protein 7.32242
KIFBP kinesin family binding protein 7.24226
ABHD4 abhydrolase domain containing 4 6.84387
MVP major vault protein 6.74989
STX1A syntaxin 1A (brain) 6.74009
FOSL1 FOS-like antigen 1 6.45072
VAT1 vesicle amine transport 1 6.43158
CIAO3 cytosolic iron-sulfur assembly component 3 6.39328
TIMP2 TIMP metallopeptidase inhibitor 2 6.2562
E2F2 E2F transcription factor 2 6.09894
NANOS3 nanos homolog 3 (Drosophila) 5.93437
DYNLT3 dynein, light chain, Tctex-type 3 5.85518
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 5.26306
ZFP36 ZFP36 ring finger protein 5.24982
SQSTM1 sequestosome 1 5.20819
PPARG peroxisome proliferator-activated receptor gamma 5.09209
ALAS1 5'-aminolevulinate synthase 1 4.7166
PFKL phosphofructokinase, liver 4.64472
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.57606
ASCC3 activating signal cointegrator 1 complex subunit 3 4.54451
CNPY3 canopy FGF signaling regulator 3 4.54326
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.52862
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.51675
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 4.45229
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 4.36945
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 4.33662
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.31347
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 4.25775
PRKCD protein kinase C, delta 4.20455
RALB v-ral simian leukemia viral oncogene homolog B 4.14948
SRC SRC proto-oncogene, non-receptor tyrosine kinase 4.05298
EVL Enah/Vasp-like 4.04249
UBQLN2 ubiquilin 2 3.97742
MYC v-myc avian myelocytomatosis viral oncogene homolog 3.90236
TRIB3 tribbles pseudokinase 3 3.89135
HMOX1 heme oxygenase 1 3.87816
PNKP polynucleotide kinase 3'-phosphatase 3.76172
SMAD3 SMAD family member 3 3.61412
CSK c-src tyrosine kinase 3.57017
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.56011
IER3 immediate early response 3 3.55596
NOTCH1 notch 1 3.54744
PRR15L proline rich 15-like 3.53453
AARS1 alanyl-tRNA synthetase 1 3.48903
LCN2 lipocalin 2 3.40539
EPHA3 EPH receptor A3 3.40349
BZW2 basic leucine zipper and W2 domains 2 3.4012
MTERF3 mitochondrial transcription termination factor 3 3.39367
UGDH UDP-glucose 6-dehydrogenase 3.37766
GSTZ1 glutathione S-transferase zeta 1 3.36723
EPHB2 EPH receptor B2 3.36265
SARS1 seryl-tRNA synthetase 1 3.33537
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.27717
DDIT4 DNA-damage-inducible transcript 4 3.24995
CXCL2 chemokine (C-X-C motif) ligand 2 3.23739
GRB10 growth factor receptor-bound protein 10 3.20946
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.1922
GPC1 glypican 1 3.18682
TERF2IP telomeric repeat binding factor 2, interacting protein 3.15942
GATA2 GATA binding protein 2 3.15937
SNAP25 synaptosomal-associated protein, 25kDa 3.12774
MAP7D1 MAP7 domain containing 1 3.09968
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.09733
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.04183
ANO1 anoctamin 1, calcium activated chloride channel 3.03792
AXIN1 axin 1 3.00262
IL4R interleukin 4 receptor 2.99702
TRIB1 tribbles pseudokinase 1 2.98443
REPS2 RALBP1 associated Eps domain containing 2 2.97708
MYLK myosin light chain kinase 2.97462
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.97287
PSD3 pleckstrin and Sec7 domain containing 3 2.96555
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.91011
IGFBP3 insulin-like growth factor binding protein 3 2.90351
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.86988
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.86713
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.85083
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.83108
KLHL21 kelch-like family member 21 2.82701
ADRB2 adrenoceptor beta 2, surface 2.79816
CBR3 carbonyl reductase 3 2.78786
LSR lipolysis stimulated lipoprotein receptor 2.78444
MAP7 microtubule-associated protein 7 2.77578
KEAP1 kelch-like ECH-associated protein 1 2.76695
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.74875
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.73925
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.73282
SFXN3 sideroflexin 3 2.72439
CAB39 calcium binding protein 39 2.71863
ACOT9 acyl-CoA thioesterase 9 2.71501
YARS1 tyrosyl-tRNA synthetase 1 2.70948
SFTPB surfactant protein B 2.6956
XPC xeroderma pigmentosum, complementation group C 2.68514
NALF1 NALCN channel auxiliary factor 1 2.63004
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.62446
IFT57 intraflagellar transport 57 2.62396
HLA-DMA major histocompatibility complex, class II, DM alpha 2.61895
PLXNB3 plexin B3 2.60547
NFASC neurofascin 2.58928
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.58268
RNF220 ring finger protein 220 2.58259
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.57738
GATA3 GATA binding protein 3 2.56681
CCL2 chemokine (C-C motif) ligand 2 2.52729
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.52631
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.51734
PRKCQ protein kinase C, theta 2.502
PROCR protein C receptor, endothelial 2.50179
MBNL2 muscleblind-like splicing regulator 2 2.4783
DUSP6 dual specificity phosphatase 6 2.47686
ANKRD11 ankyrin repeat domain 11 2.47679
HABP4 hyaluronan binding protein 4 2.46967
ZBTB20 zinc finger and BTB domain containing 20 2.46767
LGSN lengsin, lens protein with glutamine synthetase domain 2.44903
EDC3 enhancer of mRNA decapping 3 2.44899
NPC1 Niemann-Pick disease, type C1 2.44055
GARS1 glycyl-tRNA synthetase 1 2.42072
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.40885
CGRRF1 cell growth regulator with ring finger domain 1 2.39131
THSD7A thrombospondin, type I, domain containing 7A 2.36646
BAD BCL2-associated agonist of cell death 2.35907
CASC3 cancer susceptibility candidate 3 2.35608
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.35373
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.34472
SOX4 SRY (sex determining region Y)-box 4 2.33353
LRP1B low density lipoprotein receptor-related protein 1B 2.33103
NPDC1 neural proliferation, differentiation and control, 1 2.32887
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.32414
BMPR1B bone morphogenetic protein receptor, type IB 2.32311
PCDHB11 protocadherin beta 11 2.32178
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.31688
ATF3 activating transcription factor 3 2.31535
RIOX2 ribosomal oxygenase 2 2.31487
PARP6 poly (ADP-ribose) polymerase family, member 6 2.30444
RUNDC3A RUN domain containing 3A 2.29337
SLC75A1 solute carrier family 75 member 1 2.29088
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.28535
ULK1 unc-51 like autophagy activating kinase 1 2.28274
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.2721
MMRN2 multimerin 2 2.27186
ELMO2 engulfment and cell motility 2 2.26697
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.26469
MAP1B microtubule-associated protein 1B 2.26424
PTPRM protein tyrosine phosphatase, receptor type, M 2.25872
RASAL2 RAS protein activator like 2 2.25035
PLEC plectin 2.24982
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.24444
LRRC32 leucine rich repeat containing 32 2.24273
OLFM4 olfactomedin 4 2.2393
TMEM50A transmembrane protein 50A 2.22666
AVEN apoptosis, caspase activation inhibitor 2.21968
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.21597
APLP1 amyloid beta (A4) precursor-like protein 1 2.20559
ITGAV integrin, alpha V 2.20512
JADE2 jade family PHD finger 2 2.20201
NSG2 neuronal vesicle trafficking associated 2 2.20151
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.19694
MEAF6 MYST/Esa1-associated factor 6 2.19358
MAN2C1 mannosidase, alpha, class 2C, member 1 2.18349
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.18127
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.17081
E4F1 E4F transcription factor 1 2.16627
IARS1 isoleucyl-tRNA synthetase 1 2.16141
CTC1 CTS telomere maintenance complex component 1 2.15673
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.15449
GTPBP2 GTP binding protein 2 2.14898
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.14301
UBA1 ubiquitin-like modifier activating enzyme 1 2.14122
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.13603
PLK3 polo-like kinase 3 2.1293
PLCL1 phospholipase C-like 1 2.12357
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.12286
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.12245
USH1C Usher syndrome 1C (autosomal recessive, severe) 2.12235
DIPK1A divergent protein kinase domain 1A 2.11497
FBXO2 F-box protein 2 2.11469
SLC35F6 solute carrier family 35, member F6 2.11341
YJU2B YJU2 splicing factor homolog B 2.11257
MCPH1 microcephalin 1 2.10776
DMTF1 cyclin D binding myb-like transcription factor 1 2.09972
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 2.09918
PYGB phosphorylase, glycogen; brain 2.09715
COL4A4 collagen, type IV, alpha 4 2.09556
PEX11A peroxisomal biogenesis factor 11 alpha 2.09528
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.08738
ZBTB17 zinc finger and BTB domain containing 17 2.08431
NOVA1 neuro-oncological ventral antigen 1 2.08262
MAP1S microtubule-associated protein 1S 2.07832
ANO10 anoctamin 10 2.07739
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.07734
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 2.06581
CALCOCO2 calcium binding and coiled-coil domain 2 2.06574
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.06234
SYTL2 synaptotagmin-like 2 2.06225
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.05956
ZMYM2 zinc finger, MYM-type 2 2.05515
RGS11 regulator of G-protein signaling 11 2.05419
RAB23 RAB23, member RAS oncogene family 2.05338
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.05332
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.04801
LARP6 La ribonucleoprotein domain family, member 6 2.04668
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.04649
CDC25B cell division cycle 25B 2.04041
PCDHB16 protocadherin beta 16 2.03962
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.03691
STAP2 signal transducing adaptor family member 2 2.02933
TRABD TraB domain containing 2.02076
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.0175
WBP4 WW domain binding protein 4 2.016
TAOK3 TAO kinase 3 2.01392
DCTN1 dynactin 1 2.01195
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 2.00685
TBC1D19 TBC1 domain family, member 19 2.00233
CUEDC1 CUE domain containing 1 2.00031

decreased expression

Symbol Name Standardized Value
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -10.0
PSRC1 proline/serine-rich coiled-coil 1 -8.37562
B4GAT1 beta-1,4-glucuronyltransferase 1 -7.973
ISOC1 isochorismatase domain containing 1 -7.59703
FGFR4 fibroblast growth factor receptor 4 -7.23653
CDC20 cell division cycle 20 -7.13426
MELK maternal embryonic leucine zipper kinase -6.8976
RFC2 replication factor C (activator 1) 2, 40kDa -6.84017
ALDOC aldolase C, fructose-bisphosphate -6.80704
PEG10 paternally expressed 10 -6.73669
KDM3A lysine (K)-specific demethylase 3A -6.71019
ITFG1 integrin alpha FG-GAP repeat containing 1 -6.42206
TCTN1 tectonic family member 1 -6.32413
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.20547
AURKB aurora kinase B -6.1858
C5 complement component 5 -6.16268
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -5.86184
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.62802
USP6NL USP6 N-terminal like -5.5537
BIRC5 baculoviral IAP repeat containing 5 -5.38195
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.37231
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.37176
TOP2A topoisomerase (DNA) II alpha 170kDa -5.31835
SLC35F2 solute carrier family 35, member F2 -5.17734
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -5.17703
TMEM109 transmembrane protein 109 -5.05303
PGAM4 phosphoglycerate mutase family member 4 -5.05153
SOAT2 sterol O-acyltransferase 2 -5.0111
PGM1 phosphoglucomutase 1 -4.76801
TMEM97 transmembrane protein 97 -4.70306
NUP85 nucleoporin 85kDa -4.67854
PECR peroxisomal trans-2-enoyl-CoA reductase -4.60945
CCNA2 cyclin A2 -4.6082
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.57554
CCNB2 cyclin B2 -4.54363
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.45471
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -4.33637
RBM15B RNA binding motif protein 15B -4.1929
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -4.13612
HSPB1 heat shock 27kDa protein 1 -4.0617
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -4.0266
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.9742
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.94874
PCNA proliferating cell nuclear antigen -3.91712
GOLT1B golgi transport 1B -3.86184
CDK1 cyclin-dependent kinase 1 -3.79464
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.7718
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.68259
TM9SF3 transmembrane 9 superfamily member 3 -3.68091
AURKA aurora kinase A -3.67097
ECH1 enoyl CoA hydratase 1, peroxisomal -3.64974
NT5DC2 5'-nucleotidase domain containing 2 -3.59358
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.56253
HMGA2 high mobility group AT-hook 2 -3.54884
DCK deoxycytidine kinase -3.50559
ZNF274 zinc finger protein 274 -3.47166
UBE2C ubiquitin-conjugating enzyme E2C -3.38712
TSPAN4 tetraspanin 4 -3.35841
PLK1 polo-like kinase 1 -3.32118
HAT1 histone acetyltransferase 1 -3.30242
FANCG Fanconi anemia, complementation group G -3.29836
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.27923
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.27765
STMN1 stathmin 1 -3.25513
KIF14 kinesin family member 14 -3.24395
CCNB1 cyclin B1 -3.22681
TRIP13 thyroid hormone receptor interactor 13 -3.22173
EIF5 eukaryotic translation initiation factor 5 -3.20974
MLEC malectin -3.1995
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.12993
MYL9 myosin, light chain 9, regulatory -3.11403
AMDHD2 amidohydrolase domain containing 2 -3.1023
MSH6 mutS homolog 6 -3.09637
CD320 CD320 molecule -3.06032
CENPX centromere protein X -3.0523
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.02097
CHEK2 checkpoint kinase 2 -3.00528
OIP5 Opa interacting protein 5 -2.90424
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.88988
CDC6 cell division cycle 6 -2.88496
PCCB propionyl CoA carboxylase, beta polypeptide -2.88174
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.87339
HADH hydroxyacyl-CoA dehydrogenase -2.8616
LBR lamin B receptor -2.83715
KHK ketohexokinase (fructokinase) -2.82914
FEN1 flap structure-specific endonuclease 1 -2.82325
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.80354
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.80157
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.78062
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.76981
NCAPD2 non-SMC condensin I complex, subunit D2 -2.76755
MSMO1 methylsterol monooxygenase 1 -2.75117
FBXO5 F-box protein 5 -2.72912
KIF11 kinesin family member 11 -2.72769
RPIA ribose 5-phosphate isomerase A -2.72588
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.7253
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.71412
PIMREG PICALM interacting mitotic regulator -2.70971
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.70342
VAV3 vav 3 guanine nucleotide exchange factor -2.63397
ASF1B anti-silencing function 1B histone chaperone -2.62908
TBC1D10C TBC1 domain family, member 10C -2.61424
RAD51AP1 RAD51 associated protein 1 -2.59992
DONSON downstream neighbor of SON -2.59873
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.58827
CENPA centromere protein A -2.56818
DBF4 DBF4 zinc finger -2.55929
TK1 thymidine kinase 1, soluble -2.55033
MCM10 minichromosome maintenance complex component 10 -2.54205
PXMP2 peroxisomal membrane protein 2, 22kDa -2.53414
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.51864
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.51109
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -2.51071
IFITM2 interferon induced transmembrane protein 2 -2.51033
MSH2 mutS homolog 2 -2.50973
ORC6 origin recognition complex, subunit 6 -2.49574
DENND2D DENN/MADD domain containing 2D -2.48143
SMC4 structural maintenance of chromosomes 4 -2.47908
GMNN geminin, DNA replication inhibitor -2.46857
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.46352
TLR4 toll-like receptor 4 -2.45694
TMEM41B transmembrane protein 41B -2.4427
DRC9 dynein regulatory complex subunit 9 -2.43787
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.4373
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.43354
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.41514
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -2.41378
KIF15 kinesin family member 15 -2.41048
PIPOX pipecolic acid oxidase -2.40156
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.39544
EIF4A3 eukaryotic translation initiation factor 4A3 -2.39238
ECT2 epithelial cell transforming 2 -2.39166
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.38199
ELP5 elongator acetyltransferase complex subunit 5 -2.36885
PLK2 polo-like kinase 2 -2.35354
CDC25A cell division cycle 25A -2.34928
GEMIN6 gem (nuclear organelle) associated protein 6 -2.34028
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.33758
DENND2B DENN domain containing 2B -2.33721
TMX1 thioredoxin-related transmembrane protein 1 -2.33347
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.32906
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.3205
TEDC2 tubulin epsilon and delta complex 2 -2.31086
S100A4 S100 calcium binding protein A4 -2.2954
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.29354
KIF4A kinesin family member 4A -2.28958
GPR18 G protein-coupled receptor 18 -2.2791
GATA4 GATA binding protein 4 -2.27555
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.26625
DERA deoxyribose-phosphate aldolase (putative) -2.2598
OXA1L oxidase (cytochrome c) assembly 1-like -2.25914
GTF2A1 general transcription factor IIA, 1, 19/37kDa -2.2564
TFRC transferrin receptor -2.24933
TSPAN31 tetraspanin 31 -2.24683
TERT telomerase reverse transcriptase -2.24443
PSMC3IP PSMC3 interacting protein -2.23978
SAA4 serum amyloid A4, constitutive -2.23781
SLC30A10 solute carrier family 30, member 10 -2.22367
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.22352
MIS18A MIS18 kinetochore protein A -2.21575
HSPA14 heat shock 70kDa protein 14 -2.21129
STIL SCL/TAL1 interrupting locus -2.20238
CYB5R1 cytochrome b5 reductase 1 -2.2001
LDHC lactate dehydrogenase C -2.17952
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.17944
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.17777
ERCC6L excision repair cross-complementation group 6-like -2.16973
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.16939
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.16918
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.16245
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.16226
ENOPH1 enolase-phosphatase 1 -2.15288
SPC25 SPC25, NDC80 kinetochore complex component -2.13912
CDKN3 cyclin-dependent kinase inhibitor 3 -2.12795
TENT5C terminal nucleotidyltransferase 5C -2.12663
FBXO11 F-box protein 11 -2.1229
M6PR mannose-6-phosphate receptor (cation dependent) -2.11911
TFDP1 transcription factor Dp-1 -2.11399
SQLE squalene epoxidase -2.11108
GTF2A2 general transcription factor IIA, 2, 12kDa -2.10816
SESN1 sestrin 1 -2.10766
NEMP1 nuclear envelope integral membrane protein 1 -2.10555
NUCB2 nucleobindin 2 -2.10414
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.10154
DSCC1 DNA replication and sister chromatid cohesion 1 -2.10144
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -2.10048
MRPS7 mitochondrial ribosomal protein S7 -2.0906
CKS1B CDC28 protein kinase regulatory subunit 1B -2.08706
AQP5 aquaporin 5 -2.08449
LOC124907782 dual specificity protein phosphatase 22 -2.08238
FNDC11 fibronectin type III domain containing 11 -2.07652
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.07309
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.07162
RNF123 ring finger protein 123 -2.06652
KLHDC2 kelch domain containing 2 -2.06612
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.06194
GTPBP3 GTP binding protein 3 (mitochondrial) -2.06058
YME1L1 YME1-like 1 ATPase -2.05783
PDIA4 protein disulfide isomerase family A, member 4 -2.0531
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.04954
TSNAXIP1 translin-associated factor X interacting protein 1 -2.04791
TMEM248 transmembrane protein 248 -2.04692
RBM38 RNA binding motif protein 38 -2.04684
EMC6 ER membrane protein complex subunit 6 -2.04374
PARP1 poly (ADP-ribose) polymerase 1 -2.04165
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.03701
RACGAP1 Rac GTPase activating protein 1 -2.03261
POLR1G RNA polymerase I subunit G -2.03013
SGCE sarcoglycan, epsilon -2.02595
TMEM106C transmembrane protein 106C -2.02256
TTC38 tetratricopeptide repeat domain 38 -2.0193
MYL4 myosin, light chain 4, alkali; atrial, embryonic -2.01406
TMED2 transmembrane emp24 domain trafficking protein 2 -2.01364
SRSF9 serine/arginine-rich splicing factor 9 -2.01081
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.01019
THOP1 thimet oligopeptidase 1 -2.00715
TGIF2 TGFB-induced factor homeobox 2 -2.00511
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.00268