| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tris(2-chloroethyl) phosphate 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
74 genes differentially expressed following the CRCGN010_HEPG2_24H:M01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 7.85105 |
| EPHB2 | EPH receptor B2 | 5.46655 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 5.2006 |
| SQOR | sulfide quinone oxidoreductase | 5.1136 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.98155 |
| MYLK | myosin light chain kinase | 4.8174 |
| E2F2 | E2F transcription factor 2 | 4.7679 |
| MICALL1 | MICAL-like 1 | 4.52793 |
| UBQLN2 | ubiquilin 2 | 4.40225 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.35904 |
| NMU | neuromedin U | 4.32125 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.2645 |
| LOC122526780 | uncharacterized LOC122526780 | 3.9831 |
| HSPA8 | heat shock 70kDa protein 8 | 3.5275 |
| ZFP36 | ZFP36 ring finger protein | 3.47035 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.40695 |
| KIF5C | kinesin family member 5C | 3.33035 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.24365 |
| HYOU1 | hypoxia up-regulated 1 | 3.1764 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.86433 |
| CCNH | cyclin H | 2.69915 |
| PLSCR3 | phospholipid scramblase 3 | 2.64437 |
| HBA1 | hemoglobin, alpha 1 | 2.51356 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.51082 |
| CCNF | cyclin F | 2.49043 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.48173 |
| PRR15L | proline rich 15-like | 2.4617 |
| GPATCH8 | G patch domain containing 8 | 2.41153 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.408 |
| SMAD3 | SMAD family member 3 | 2.37178 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 2.27545 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.2335 |
| CYCS | cytochrome c, somatic | 2.224 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 2.2191 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 2.15545 |
| EPHA3 | EPH receptor A3 | 2.09108 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 2.0845 |
| RPA3 | replication protein A3, 14kDa | 2.08145 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 2.07715 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 2.04105 |
| BCL2L2 | BCL2-like 2 | 2.01205 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.18835 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.09045 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.88685 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.8156 |
| TRIB3 | tribbles pseudokinase 3 | -4.7207 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.68185 |
| SCAND1 | SCAN domain containing 1 | -4.51315 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.20585 |
| TLCD3A | TLC domain containing 3A | -3.55725 |
| GLOD4 | glyoxalase domain containing 4 | -3.45285 |
| SNX11 | sorting nexin 11 | -3.40158 |
| HEATR1 | HEAT repeat containing 1 | -3.10445 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.05835 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -2.95035 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | -2.88217 |
| PEG10 | paternally expressed 10 | -2.87603 |
| TWF2 | twinfilin actin binding protein 2 | -2.82565 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.77505 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.5433 |
| FAT1 | FAT atypical cadherin 1 | -2.53805 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.50723 |
| TLR4 | toll-like receptor 4 | -2.3259 |
| TENT5A | terminal nucleotidyltransferase 5A | -2.14125 |
| MICU1 | mitochondrial calcium uptake 1 | -2.12315 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.11773 |
| STBD1 | starch binding domain 1 | -2.10435 |
| C4BPB | complement component 4 binding protein, beta | -2.0986 |
| FMO5 | flavin containing monooxygenase 5 | -2.08923 |
| CYBRD1 | cytochrome b reductase 1 | -2.05675 |
| PLGLB2 | plasminogen-like B2 | -2.05167 |
| C5 | complement component 5 | -2.0511 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -2.02135 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -2.01255 |
