CRCGN010_HEPG2_24H:M02 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.69804
|
|
MAP7
|
microtubule-associated protein 7
|
6.07026
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.60451
|
|
VGLL4
|
vestigial-like family member 4
|
4.58016
|
|
LAGE3
|
L antigen family, member 3
|
4.34946
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
4.05245
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.72496
|
|
FAM20B
|
family with sequence similarity 20, member B
|
3.62896
|
|
STIMATE
|
STIM activating enhancer
|
3.45909
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.42188
|
|
KIF5C
|
kinesin family member 5C
|
3.41966
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.40307
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.04585
|
|
PTK2
|
protein tyrosine kinase 2
|
2.91953
|
|
CHN1
|
chimerin 1
|
2.68551
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.54033
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.39228
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.39106
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.36919
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.32837
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.32825
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.31384
|
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3
|
2.22574
|
|
CBR3
|
carbonyl reductase 3
|
2.21877
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.13008
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.11948
|
|
CAMTA2
|
calmodulin binding transcription activator 2
|
2.04773
|
|
EPHA3
|
EPH receptor A3
|
2.04141
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-7.03649
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.83099
|
|
CDC20
|
cell division cycle 20
|
-5.18242
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.95865
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.52479
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.29057
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.1393
|
|
TLR4
|
toll-like receptor 4
|
-3.67913
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.64943
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.45591
|
|
VAT1
|
vesicle amine transport 1
|
-3.45523
|
|
GNAS
|
GNAS complex locus
|
-3.36571
|
|
GLOD4
|
glyoxalase domain containing 4
|
-3.21354
|
|
THAP11
|
THAP domain containing 11
|
-3.07858
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.07016
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.01569
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.88927
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.82775
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.7867
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.76183
|
|
WASHC4
|
WASH complex subunit 4
|
-2.51325
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.50292
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.20745
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.13755
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.13352
|
|
CD58
|
CD58 molecule
|
-2.0215
|
