CRCGN010_HEPG2_24H:M03 Gene Set
Genes
42 genes differentially expressed following the CRCGN010_HEPG2_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
4.23938
|
|
SFTPB
|
surfactant protein B
|
3.83012
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.6372
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.46938
|
|
RRAGA
|
Ras-related GTP binding A
|
3.3118
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.22095
|
|
NMU
|
neuromedin U
|
3.04695
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.02646
|
|
STXBP2
|
syntaxin binding protein 2
|
2.67158
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.54075
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.50255
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.44673
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.3498
|
|
HBA1
|
hemoglobin, alpha 1
|
2.28383
|
|
RPL39
|
ribosomal protein L39
|
2.25724
|
|
PRR15L
|
proline rich 15-like
|
2.25227
|
|
COMMD1
|
copper metabolism (Murr1) domain containing 1
|
2.22777
|
|
CRTAP
|
cartilage associated protein
|
2.21455
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.10154
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.07958
|
|
RPS12
|
ribosomal protein S12
|
2.06092
|
|
CHN1
|
chimerin 1
|
2.0327
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TRIB3
|
tribbles pseudokinase 3
|
-10.0
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.84326
|
|
ZNF586
|
zinc finger protein 586
|
-4.37213
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.28666
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-4.2191
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.17038
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.15844
|
|
TLR4
|
toll-like receptor 4
|
-4.00969
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-4.00034
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.84301
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.79557
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.38507
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.31954
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.30208
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.26235
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.23715
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.88303
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.15957
|
|
PERP
|
PERP, TP53 apoptosis effector
|
-2.08562
|
|
WASHC4
|
WASH complex subunit 4
|
-2.07324
|
