CRCGN010_HEPG2_24H:M04 Gene Set
Genes
45 genes differentially expressed following the CRCGN010_HEPG2_24H:M04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
8.41094
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
8.29598
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.66076
|
|
MAP7
|
microtubule-associated protein 7
|
5.24521
|
|
ZNF589
|
zinc finger protein 589
|
5.17672
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.93436
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.73738
|
|
SLC75A1
|
solute carrier family 75 member 1
|
3.9172
|
|
PRR15L
|
proline rich 15-like
|
3.83031
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.64704
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.62396
|
|
E2F2
|
E2F transcription factor 2
|
3.62166
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.53112
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.43744
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.15745
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.92106
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.90214
|
|
VGLL4
|
vestigial-like family member 4
|
2.55454
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.35479
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.32685
|
|
GATA2
|
GATA binding protein 2
|
2.22449
|
|
ZNF84
|
zinc finger protein 84
|
2.16201
|
|
STK10
|
serine/threonine kinase 10
|
2.12389
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-5.10174
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.93802
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.88412
|
|
CCNB2
|
cyclin B2
|
-4.39144
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-4.09032
|
|
ZW10
|
zw10 kinetochore protein
|
-3.81164
|
|
RNF167
|
ring finger protein 167
|
-3.61124
|
|
GNAS
|
GNAS complex locus
|
-3.60561
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-3.51224
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.13035
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.06882
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.05876
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.93738
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.76528
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.72441
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.66371
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.55566
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.4172
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.32545
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.18214
|
|
CDC20
|
cell division cycle 20
|
-2.16288
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.14502
|
