CRCGN010_HEPG2_24H:M05 Gene Set
Genes
45 genes differentially expressed following the CRCGN010_HEPG2_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
10.0
|
|
UBQLN2
|
ubiquilin 2
|
4.47413
|
|
HYOU1
|
hypoxia up-regulated 1
|
4.37523
|
|
AXIN1
|
axin 1
|
4.37396
|
|
CYCS
|
cytochrome c, somatic
|
4.08278
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.93929
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.63647
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.50472
|
|
IDE
|
insulin-degrading enzyme
|
3.22014
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
3.17256
|
|
MAP7
|
microtubule-associated protein 7
|
2.95525
|
|
RPL39L
|
ribosomal protein L39-like
|
2.94919
|
|
MEST
|
mesoderm specific transcript
|
2.92116
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.8855
|
|
CSK
|
c-src tyrosine kinase
|
2.79968
|
|
PLS1
|
plastin 1
|
2.71346
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.68347
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.54667
|
|
NMU
|
neuromedin U
|
2.49994
|
|
CRTAP
|
cartilage associated protein
|
2.39271
|
|
H2BC12
|
H2B clustered histone 12
|
2.3489
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.32983
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.27056
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.20744
|
|
HSPA8
|
heat shock 70kDa protein 8
|
2.20535
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.17865
|
|
OAS1
|
2'-5'-oligoadenylate synthetase 1, 40/46kDa
|
2.17575
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.11347
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.10588
|
|
GPATCH8
|
G patch domain containing 8
|
2.0705
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
2.05859
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.74504
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.61872
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.48921
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.73728
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.72469
|
|
GNAS
|
GNAS complex locus
|
-3.16103
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.15323
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.90428
|
|
CAB39
|
calcium binding protein 39
|
-2.78985
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.59068
|
|
ERC1
|
ELKS/RAB6-interacting/CAST family member 1
|
-2.3581
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.26479
|
|
SCMH1
|
sex comb on midleg homolog 1 (Drosophila)
|
-2.01209
|
|
TNS4
|
tensin 4
|
-2.0041
|
