| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tris(2-chloroethyl) phosphate 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN010_HEPG2_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 10.0 |
| STAP2 | signal transducing adaptor family member 2 | 4.9835 |
| CHMP6 | charged multivesicular body protein 6 | 4.73936 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.67822 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.54095 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.40671 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 4.07917 |
| PRKCH | protein kinase C, eta | 3.3125 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.81904 |
| H2BC12 | H2B clustered histone 12 | 2.78703 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.7032 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.66459 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.61756 |
| EVL | Enah/Vasp-like | 2.53086 |
| TCIM | transcriptional and immune response regulator | 2.4973 |
| NOSIP | nitric oxide synthase interacting protein | 2.38451 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.38147 |
| CHN1 | chimerin 1 | 2.29648 |
| RAB21 | RAB21, member RAS oncogene family | 2.28815 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.26737 |
| MEOX2 | mesenchyme homeobox 2 | 2.14446 |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 | 2.10867 |
| ZNF432 | zinc finger protein 432 | 2.08243 |
| BAX | BCL2-associated X protein | 2.06664 |
| ZNF140 | zinc finger protein 140 | 2.05624 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.04328 |
| JADE2 | jade family PHD finger 2 | 2.01463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIB3 | tribbles pseudokinase 3 | -9.02936 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.7934 |
| PCNA | proliferating cell nuclear antigen | -4.67821 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.58291 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.58277 |
| ADI1 | acireductone dioxygenase 1 | -4.47509 |
| LDHD | lactate dehydrogenase D | -4.41881 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -4.35354 |
| TLCD3A | TLC domain containing 3A | -3.87894 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.85679 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.59489 |
| YME1L1 | YME1-like 1 ATPase | -3.19044 |
| TCTN1 | tectonic family member 1 | -3.06678 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.04972 |
| CAB39 | calcium binding protein 39 | -3.00886 |
| NGRN | neugrin, neurite outgrowth associated | -2.73915 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.70383 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.68197 |
| MTA1 | metastasis associated 1 | -2.63922 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.52711 |
| GNAS | GNAS complex locus | -2.38953 |
| COBL | cordon-bleu WH2 repeat protein | -2.33125 |
| FANCE | Fanconi anemia, complementation group E | -2.30618 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.19876 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -2.1742 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -2.13877 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | -2.12279 |
| EMILIN1 | elastin microfibril interfacer 1 | -2.08294 |
| BLCAP | bladder cancer associated protein | -2.06389 |
