| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ditiocarb-sodium-trihydrate 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN010_HEPG2_24H:M07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 6.74581 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.77465 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.51733 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 4.73229 |
| KIFBP | kinesin family binding protein | 4.27235 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.17878 |
| ATP11B | ATPase, class VI, type 11B | 4.04233 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.98329 |
| CYCS | cytochrome c, somatic | 3.91079 |
| BIRC2 | baculoviral IAP repeat containing 2 | 3.82741 |
| E2F2 | E2F transcription factor 2 | 3.76901 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.40103 |
| EPHA3 | EPH receptor A3 | 3.39988 |
| EPHB2 | EPH receptor B2 | 3.34293 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.33733 |
| MYLK | myosin light chain kinase | 3.29807 |
| SFTPB | surfactant protein B | 3.26003 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.15942 |
| CHN1 | chimerin 1 | 3.09812 |
| MAP7 | microtubule-associated protein 7 | 2.70574 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.67045 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.51884 |
| CTSL | cathepsin L | 2.51594 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.48434 |
| KIF5C | kinesin family member 5C | 2.41517 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 | 2.38642 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.36585 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.31675 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.25019 |
| RRAGA | Ras-related GTP binding A | 2.23142 |
| CSK | c-src tyrosine kinase | 2.19374 |
| TXNRD1 | thioredoxin reductase 1 | 2.16813 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.16744 |
| CHMP6 | charged multivesicular body protein 6 | 2.167 |
| NCF1 | neutrophil cytosolic factor 1 | 2.0944 |
| ATAD3A | ATPase family, AAA domain containing 3A | 2.05425 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.03434 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.63389 |
| HSPB1 | heat shock 27kDa protein 1 | -6.39495 |
| FGFR4 | fibroblast growth factor receptor 4 | -5.88162 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.00945 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.43827 |
| TRIB3 | tribbles pseudokinase 3 | -4.06969 |
| LDHD | lactate dehydrogenase D | -3.9467 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.93143 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.8261 |
| ZNF586 | zinc finger protein 586 | -3.80672 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.794 |
| CD320 | CD320 molecule | -3.23403 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.22061 |
| PLK1 | polo-like kinase 1 | -3.11271 |
| TUBB6 | tubulin, beta 6 class V | -2.98629 |
| TLCD3A | TLC domain containing 3A | -2.9224 |
| FAIM | Fas apoptotic inhibitory molecule | -2.82468 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.81315 |
| XPO7 | exportin 7 | -2.66285 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.65312 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.59593 |
| PPOX | protoporphyrinogen oxidase | -2.57811 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.47172 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.4709 |
| RGS2 | regulator of G-protein signaling 2 | -2.25723 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.24192 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.22529 |
| NGRN | neugrin, neurite outgrowth associated | -2.20724 |
| TLR4 | toll-like receptor 4 | -2.16462 |
| GNAS | GNAS complex locus | -2.06176 |
| ENTREP1 | endosomal transmembrane epsin interactor 1 | -2.05099 |
