CRCGN010_HEPG2_24H:M08 Gene Set
Genes
48 genes differentially expressed following the CRCGN010_HEPG2_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
7.90485
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.44997
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
4.50602
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.2548
|
|
LCN2
|
lipocalin 2
|
4.04767
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.85672
|
|
UBQLN2
|
ubiquilin 2
|
3.72834
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.36183
|
|
NUP133
|
nucleoporin 133kDa
|
3.28828
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.87494
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.74628
|
|
GATA2
|
GATA binding protein 2
|
2.64297
|
|
TNFSF8
|
tumor necrosis factor (ligand) superfamily, member 8
|
2.43829
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.40294
|
|
KRT12
|
keratin 12, type I
|
2.39737
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.34608
|
|
HEBP1
|
heme binding protein 1
|
2.30359
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.27915
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.26264
|
|
GALT
|
galactose-1-phosphate uridylyltransferase
|
2.16423
|
|
PGLYRP1
|
peptidoglycan recognition protein 1
|
2.15305
|
|
CEBPE
|
CCAAT/enhancer binding protein (C/EBP), epsilon
|
2.12553
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.10706
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.06755
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
2.03553
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.01033
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.7533
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-5.72916
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.87288
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.84347
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.43394
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.3996
|
|
TSPAN4
|
tetraspanin 4
|
-4.05307
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.40369
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.16843
|
|
SNX11
|
sorting nexin 11
|
-3.08744
|
|
DCK
|
deoxycytidine kinase
|
-3.08368
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.82514
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.7599
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.62196
|
|
GNAS
|
GNAS complex locus
|
-2.49502
|
|
WASHC4
|
WASH complex subunit 4
|
-2.44059
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.43646
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.3654
|
|
USP6NL
|
USP6 N-terminal like
|
-2.30884
|
|
THAP11
|
THAP domain containing 11
|
-2.2807
|
|
DSG2
|
desmoglein 2
|
-2.14221
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.10242
|
