| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ditiocarb-sodium-trihydrate 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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77 genes differentially expressed following the CRCGN010_HEPG2_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 5.9691 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.65512 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.64909 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.54493 |
| MSRA | methionine sulfoxide reductase A | 4.52496 |
| EPHB2 | EPH receptor B2 | 4.5193 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.34059 |
| CCDC92 | coiled-coil domain containing 92 | 4.27477 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.23511 |
| CHMP6 | charged multivesicular body protein 6 | 4.1678 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.10753 |
| E2F2 | E2F transcription factor 2 | 4.03521 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.68707 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.60625 |
| FZD7 | frizzled class receptor 7 | 3.37778 |
| MEST | mesoderm specific transcript | 3.31859 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.29628 |
| NOTCH1 | notch 1 | 3.26403 |
| CSK | c-src tyrosine kinase | 3.18161 |
| ABHD4 | abhydrolase domain containing 4 | 3.17875 |
| PRR15L | proline rich 15-like | 3.17123 |
| KLHL9 | kelch-like family member 9 | 3.10608 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.91938 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.65687 |
| CEP57 | centrosomal protein 57kDa | 2.6185 |
| GPATCH8 | G patch domain containing 8 | 2.53892 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.4694 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.45483 |
| CCNF | cyclin F | 2.43076 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.25373 |
| FCHO1 | FCH domain only 1 | 2.25074 |
| SIRT3 | sirtuin 3 | 2.16093 |
| DMXL1 | Dmx-like 1 | 2.14793 |
| SLC35B1 | solute carrier family 35, member B1 | 2.12926 |
| CD81 | CD81 molecule | 2.1147 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) | 2.05663 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.03902 |
| NKX3-2 | NK3 homeobox 2 | 2.03511 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.03384 |
| TGM4 | transglutaminase 4 | 2.03358 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NGRN | neugrin, neurite outgrowth associated | -5.22205 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.9151 |
| PCNA | proliferating cell nuclear antigen | -4.688 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.58429 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.55526 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.47685 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.43982 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.41545 |
| HMG20B | high mobility group 20B | -4.39011 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.27683 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.21639 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.10702 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.01744 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.65485 |
| TLR4 | toll-like receptor 4 | -3.44877 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.37538 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.15464 |
| THAP11 | THAP domain containing 11 | -2.99207 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.99169 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.74976 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.65233 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.63928 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.56665 |
| TCTN1 | tectonic family member 1 | -2.54454 |
| TSPAN4 | tetraspanin 4 | -2.49515 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.33956 |
| DBNDD2 | dysbindin (dystrobrevin binding protein 1) domain containing 2 | -2.29653 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.29432 |
| CHMP4B | charged multivesicular body protein 4B | -2.27804 |
| ADI1 | acireductone dioxygenase 1 | -2.22631 |
| PDLIM1 | PDZ and LIM domain 1 | -2.20515 |
| RNF167 | ring finger protein 167 | -2.1962 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.17061 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.16866 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.11352 |
| SEPTIN10 | septin 10 | -2.1008 |
| CCNB2 | cyclin B2 | -2.03843 |
