CRCGN010_HEPG2_24H:M10 Gene Set
Genes
51 genes differentially expressed following the CRCGN010_HEPG2_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
VGLL4
|
vestigial-like family member 4
|
5.36525
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.17939
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.42293
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.29733
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.69974
|
|
MAP7
|
microtubule-associated protein 7
|
3.67031
|
|
STIMATE
|
STIM activating enhancer
|
3.43598
|
|
CCNA1
|
cyclin A1
|
3.16102
|
|
PRKCH
|
protein kinase C, eta
|
3.14406
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.09072
|
|
PMM2
|
phosphomannomutase 2
|
3.00293
|
|
PLOD3
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
|
2.93392
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.82561
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.75339
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.6424
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.58743
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.54963
|
|
CYCS
|
cytochrome c, somatic
|
2.53569
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.42492
|
|
CHEK2
|
checkpoint kinase 2
|
2.37753
|
|
CEP57
|
centrosomal protein 57kDa
|
2.3259
|
|
SIRT3
|
sirtuin 3
|
2.30664
|
|
LAG3
|
lymphocyte-activation gene 3
|
2.14028
|
|
GRAMD2B
|
GRAM domain containing 2B
|
2.02961
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.02327
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-9.03125
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-5.49902
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-4.85654
|
|
CDC20
|
cell division cycle 20
|
-4.43932
|
|
CCNB2
|
cyclin B2
|
-4.29269
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.26424
|
|
DSG2
|
desmoglein 2
|
-4.13537
|
|
LDHD
|
lactate dehydrogenase D
|
-4.01104
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.00766
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.85421
|
|
LYPLA1
|
lysophospholipase I
|
-3.75701
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.66876
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.20628
|
|
GNAS
|
GNAS complex locus
|
-3.18774
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.15152
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.0367
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.02432
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.96555
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.84338
|
|
WASHC4
|
WASH complex subunit 4
|
-2.83127
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.60115
|
|
NVL
|
nuclear VCP-like
|
-2.45482
|
|
SCAND1
|
SCAN domain containing 1
|
-2.1555
|
|
UBAC1
|
UBA domain containing 1
|
-2.14533
|
|
TLR4
|
toll-like receptor 4
|
-2.05672
|
|
ZW10
|
zw10 kinetochore protein
|
-2.01188
|
