| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ditiocarb-sodium-trihydrate 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN010_HEPG2_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 7.05888 |
| MAP7 | microtubule-associated protein 7 | 5.56104 |
| UBQLN2 | ubiquilin 2 | 4.53024 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.36087 |
| LCN2 | lipocalin 2 | 4.30458 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.25856 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.05838 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.97038 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.58776 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.48427 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.36494 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.18736 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.12355 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.96073 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.92492 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.81014 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.68185 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.55795 |
| MSRA | methionine sulfoxide reductase A | 2.48507 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.46616 |
| MEF2C | myocyte enhancer factor 2C | 2.46549 |
| JADE2 | jade family PHD finger 2 | 2.46114 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.42837 |
| KIF5C | kinesin family member 5C | 2.42402 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.40317 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.34915 |
| FOXN2 | forkhead box N2 | 2.25434 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.2431 |
| PRKCQ | protein kinase C, theta | 2.24179 |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | 2.21814 |
| RPA3 | replication protein A3, 14kDa | 2.20116 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.17905 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 2.16368 |
| CYCS | cytochrome c, somatic | 2.06934 |
| SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 2.05943 |
| DIPK1A | divergent protein kinase domain 1A | 2.03651 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -10.0 |
| TRIB3 | tribbles pseudokinase 3 | -7.04201 |
| PCNA | proliferating cell nuclear antigen | -6.69831 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.89535 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.79667 |
| CDC20 | cell division cycle 20 | -4.40752 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.05911 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.0591 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.64062 |
| MTA1 | metastasis associated 1 | -3.08409 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.98697 |
| GNAS | GNAS complex locus | -2.92476 |
| PLA2G15 | phospholipase A2, group XV | -2.86698 |
| PPOX | protoporphyrinogen oxidase | -2.86064 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.7071 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.62982 |
| PRPF4 | pre-mRNA processing factor 4 | -2.55289 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.54225 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.52954 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.51486 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.44867 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.25526 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.24904 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.228 |
| LDHD | lactate dehydrogenase D | -2.21644 |
| SGSH | N-sulfoglucosamine sulfohydrolase | -2.14662 |
| HAT1 | histone acetyltransferase 1 | -2.12287 |
| TXNDC9 | thioredoxin domain containing 9 | -2.07576 |
| NGRN | neugrin, neurite outgrowth associated | -2.02378 |
| INTS14 | integrator complex subunit 14 | -2.01743 |
