CRCGN010_HEPG2_24H:M12 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
7.73895
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.14476
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.49854
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.09146
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.96933
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.82852
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.50759
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.47022
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.1041
|
|
CHEK2
|
checkpoint kinase 2
|
3.06386
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.9561
|
|
EPHA3
|
EPH receptor A3
|
2.92627
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.86667
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.77416
|
|
LCN2
|
lipocalin 2
|
2.71471
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.70165
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.64333
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.5454
|
|
H2BC12
|
H2B clustered histone 12
|
2.38418
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.36691
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.35999
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
2.28214
|
|
SMAD3
|
SMAD family member 3
|
2.25772
|
|
LHX6
|
LIM homeobox 6
|
2.19453
|
|
MMP1
|
matrix metallopeptidase 1
|
2.14212
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.11664
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.0715
|
|
NUP93
|
nucleoporin 93kDa
|
2.01157
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.79446
|
|
TLR4
|
toll-like receptor 4
|
-7.18493
|
|
CCNB2
|
cyclin B2
|
-5.89299
|
|
ZNF586
|
zinc finger protein 586
|
-5.39543
|
|
PEG10
|
paternally expressed 10
|
-4.19131
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.10138
|
|
LDHD
|
lactate dehydrogenase D
|
-3.85343
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.84589
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.78156
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.71982
|
|
CDC20
|
cell division cycle 20
|
-3.62114
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.51445
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.35021
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.23012
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.22807
|
|
GNAS
|
GNAS complex locus
|
-2.90967
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.65783
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.65027
|
|
HMG20B
|
high mobility group 20B
|
-2.57159
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.51736
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.4968
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.29058
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.26999
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.26824
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.02584
|
|
NUP85
|
nucleoporin 85kDa
|
-2.01133
|
