CRCGN010_HEPG2_24H:M14 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:M14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ATP11B
|
ATPase, class VI, type 11B
|
7.00256
|
|
MAP7
|
microtubule-associated protein 7
|
6.06605
|
|
LOC122526780
|
uncharacterized LOC122526780
|
5.29722
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
4.49494
|
|
NUP133
|
nucleoporin 133kDa
|
4.17836
|
|
LCN2
|
lipocalin 2
|
3.88182
|
|
MOK
|
MOK protein kinase
|
3.63464
|
|
SIRT3
|
sirtuin 3
|
3.39729
|
|
CSK
|
c-src tyrosine kinase
|
3.30773
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.2968
|
|
CRTAP
|
cartilage associated protein
|
3.19527
|
|
HOXA10
|
homeobox A10
|
3.16223
|
|
EVL
|
Enah/Vasp-like
|
2.98626
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.90304
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.73121
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.72829
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.63618
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.51636
|
|
TSEN34
|
TSEN34 tRNA splicing endonuclease subunit
|
2.32435
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.2847
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.19745
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.07582
|
|
CHEK2
|
checkpoint kinase 2
|
2.0562
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.01101
|
|
NOTCH1
|
notch 1
|
2.0002
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.09227
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.45172
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.04285
|
|
TLR4
|
toll-like receptor 4
|
-3.89861
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.6602
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.64718
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
-3.52289
|
|
CD320
|
CD320 molecule
|
-3.51276
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-3.46179
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.39978
|
|
CAB39
|
calcium binding protein 39
|
-3.22412
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.21733
|
|
CDC20
|
cell division cycle 20
|
-3.09263
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.72276
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.64085
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.59828
|
|
DCK
|
deoxycytidine kinase
|
-2.28725
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.28495
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.15372
|
|
GNAS
|
GNAS complex locus
|
-2.13705
|
|
SNX11
|
sorting nexin 11
|
-2.06607
|
