CRCGN010_HEPG2_24H:M15 Gene Set
Genes
50 genes differentially expressed following the CRCGN010_HEPG2_24H:M15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MSRA
|
methionine sulfoxide reductase A
|
6.23888
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.49638
|
|
E2F2
|
E2F transcription factor 2
|
5.26782
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.07386
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.93907
|
|
MAP7
|
microtubule-associated protein 7
|
4.82465
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.1324
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.47326
|
|
PRKCH
|
protein kinase C, eta
|
3.42093
|
|
PLS1
|
plastin 1
|
3.40792
|
|
STIMATE
|
STIM activating enhancer
|
3.39152
|
|
GPATCH8
|
G patch domain containing 8
|
3.33117
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.32969
|
|
CSK
|
c-src tyrosine kinase
|
3.30745
|
|
IDE
|
insulin-degrading enzyme
|
3.3011
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.10338
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.85436
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.66462
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.44939
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.33913
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.32525
|
|
CDC45
|
cell division cycle 45
|
2.28064
|
|
STXBP2
|
syntaxin binding protein 2
|
2.26608
|
|
ZNF318
|
zinc finger protein 318
|
2.10234
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.08086
|
|
FTO
|
fat mass and obesity associated
|
2.0141
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-6.57294
|
|
CASC3
|
cancer susceptibility candidate 3
|
-5.26032
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.03801
|
|
CCNB2
|
cyclin B2
|
-4.54391
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.3068
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.80029
|
|
HAT1
|
histone acetyltransferase 1
|
-3.51278
|
|
ZNF586
|
zinc finger protein 586
|
-3.49076
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-3.337
|
|
TSPAN4
|
tetraspanin 4
|
-3.19991
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-3.05492
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.00691
|
|
CPNE3
|
copine III
|
-2.93655
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.90491
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.9043
|
|
TLR4
|
toll-like receptor 4
|
-2.77401
|
|
GNAS
|
GNAS complex locus
|
-2.62208
|
|
C5
|
complement component 5
|
-2.58919
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.45552
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.24963
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
-2.22855
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.19514
|
|
DNMT1
|
DNA (cytosine-5-)-methyltransferase 1
|
-2.13591
|
|
CDK5RAP1
|
CDK5 regulatory subunit associated protein 1
|
-2.03341
|
