CRCGN010_HEPG2_24H:M16 Gene Set
Genes
55 genes differentially expressed following the CRCGN010_HEPG2_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.03342
|
|
CYCS
|
cytochrome c, somatic
|
4.71515
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.24935
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.91872
|
|
CHN1
|
chimerin 1
|
3.83602
|
|
LAGE3
|
L antigen family, member 3
|
3.75316
|
|
CRTAP
|
cartilage associated protein
|
3.42558
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.9445
|
|
TEX10
|
testis expressed 10
|
2.93537
|
|
PRR15L
|
proline rich 15-like
|
2.62136
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.5541
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.52021
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.43922
|
|
CISD1
|
CDGSH iron sulfur domain 1
|
2.33249
|
|
CEP57
|
centrosomal protein 57kDa
|
2.32337
|
|
GATA2
|
GATA binding protein 2
|
2.27216
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.17409
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.13009
|
|
NTSR1
|
neurotensin receptor 1 (high affinity)
|
2.12764
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.12017
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.11386
|
|
HAT1
|
histone acetyltransferase 1
|
2.10087
|
|
NUP133
|
nucleoporin 133kDa
|
2.07433
|
|
CCDC90B
|
coiled-coil domain containing 90B
|
2.0641
|
|
SLC25A1
|
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
|
2.05105
|
|
CDO1
|
cysteine dioxygenase type 1
|
2.05036
|
|
COX5B
|
cytochrome c oxidase subunit Vb
|
2.02816
|
|
MRPL11
|
mitochondrial ribosomal protein L11
|
2.00756
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.00504
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.79217
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.70739
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.61885
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.88145
|
|
CCNB2
|
cyclin B2
|
-4.87445
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.73955
|
|
ZNF586
|
zinc finger protein 586
|
-4.30174
|
|
RNF167
|
ring finger protein 167
|
-3.88974
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.42145
|
|
MTA1
|
metastasis associated 1
|
-2.97434
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.97312
|
|
VPS54
|
vacuolar protein sorting 54 homolog (S. cerevisiae)
|
-2.71604
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.68074
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.66602
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.56239
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.48935
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.45699
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.28614
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.27915
|
|
DCK
|
deoxycytidine kinase
|
-2.08118
|
|
CPNE3
|
copine III
|
-2.06188
|
|
SLC12A9
|
solute carrier family 12, member 9
|
-2.05143
|
|
MYL9
|
myosin, light chain 9, regulatory
|
-2.04391
|
|
TRIM68
|
tripartite motif containing 68
|
-2.03565
|
|
CIC
|
capicua transcriptional repressor
|
-2.03043
|
|
MAPKBP1
|
mitogen-activated protein kinase binding protein 1
|
-2.00999
|
