CRCGN010_HEPG2_24H:M18 Gene Set
Genes
45 genes differentially expressed following the CRCGN010_HEPG2_24H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.78962
|
|
EVL
|
Enah/Vasp-like
|
5.55492
|
|
LCN2
|
lipocalin 2
|
4.64231
|
|
UBQLN2
|
ubiquilin 2
|
4.06832
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.93053
|
|
CCNA1
|
cyclin A1
|
3.85536
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.74585
|
|
GPATCH8
|
G patch domain containing 8
|
3.55935
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.49604
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.38846
|
|
KLHL9
|
kelch-like family member 9
|
3.05062
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.90057
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.66943
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.64394
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.54989
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.3419
|
|
CYCS
|
cytochrome c, somatic
|
2.29111
|
|
RRAGA
|
Ras-related GTP binding A
|
2.27633
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.25581
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.03729
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.89687
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.85299
|
|
ZNF586
|
zinc finger protein 586
|
-5.28719
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.57802
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.06816
|
|
DNM1L
|
dynamin 1-like
|
-3.96475
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.86205
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.84243
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.71398
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.70596
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.67438
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.62103
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-3.61707
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.51489
|
|
CDC20
|
cell division cycle 20
|
-3.30154
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.29693
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.21367
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.20372
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.94228
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.93613
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.83727
|
|
WDR62
|
WD repeat domain 62
|
-2.38953
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.18557
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.1021
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.06502
|
