CRCGN010_HEPG2_24H:M19 Gene Set
Genes
57 genes differentially expressed following the CRCGN010_HEPG2_24H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
8.00254
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
7.11113
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.87817
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
4.76034
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
4.42195
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.8289
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
3.4517
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.39028
|
|
CRYZ
|
crystallin, zeta (quinone reductase)
|
3.38101
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.3644
|
|
CHN1
|
chimerin 1
|
3.32756
|
|
NOTCH1
|
notch 1
|
3.23447
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.19087
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.17376
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.16134
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.15076
|
|
UBQLN2
|
ubiquilin 2
|
3.12932
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.07857
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.07733
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.98996
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.92312
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.47503
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.40516
|
|
STK10
|
serine/threonine kinase 10
|
2.3608
|
|
KLHL21
|
kelch-like family member 21
|
2.25089
|
|
PRKCH
|
protein kinase C, eta
|
2.224
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.02015
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-6.15717
|
|
ZNF586
|
zinc finger protein 586
|
-5.33139
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-4.34993
|
|
GNAS
|
GNAS complex locus
|
-4.24268
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.91091
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.76469
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.70848
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.45853
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.30344
|
|
SNX11
|
sorting nexin 11
|
-3.17874
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.07999
|
|
CDC20
|
cell division cycle 20
|
-3.00586
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.99376
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.97875
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.63058
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.57793
|
|
CAPNS1
|
calpain, small subunit 1
|
-2.52669
|
|
C5
|
complement component 5
|
-2.48078
|
|
TBX2
|
T-box 2
|
-2.47838
|
|
CNTLN
|
centlein, centrosomal protein
|
-2.42085
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.34139
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.33857
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.32774
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.2255
|
|
XPO7
|
exportin 7
|
-2.17947
|
|
LIN37
|
lin-37 DREAM MuvB core complex component
|
-2.12
|
|
TBCB
|
tubulin folding cofactor B
|
-2.07503
|
|
PEG10
|
paternally expressed 10
|
-2.07176
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.03286
|
|
USP9Y
|
ubiquitin specific peptidase 9, Y-linked
|
-2.02505
|
