CRCGN010_HEPG2_24H:M20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iodoform 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

59 genes differentially expressed following the CRCGN010_HEPG2_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 8.36396
PRKCH protein kinase C, eta 6.16319
AMDHD2 amidohydrolase domain containing 2 5.06533
CARMIL1 capping protein regulator and myosin 1 linker 1 4.62713
SQOR sulfide quinone oxidoreductase 4.61389
MAP7 microtubule-associated protein 7 4.52254
CBR3 carbonyl reductase 3 4.35564
EPHA3 EPH receptor A3 4.33243
ADRB2 adrenoceptor beta 2, surface 4.31454
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.27518
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.27065
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.1827
CXCL2 chemokine (C-X-C motif) ligand 2 3.95442
E2F2 E2F transcription factor 2 3.85332
STAP2 signal transducing adaptor family member 2 3.68696
CIAO3 cytosolic iron-sulfur assembly component 3 3.60159
INTS3 integrator complex subunit 3 3.53137
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.16868
HLA-DMA major histocompatibility complex, class II, DM alpha 3.11382
CHN1 chimerin 1 2.89836
CCL2 chemokine (C-C motif) ligand 2 2.84179
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.71995
MTERF3 mitochondrial transcription termination factor 3 2.68026
SYNDIG1 synapse differentiation inducing 1 2.48999
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.48638
ADAMDEC1 ADAM-like, decysin 1 2.39787
ARID4B AT rich interactive domain 4B (RBP1-like) 2.38546
CCNF cyclin F 2.29335
VCAM1 vascular cell adhesion molecule 1 2.22594
PRAF2 PRA1 domain family, member 2 2.18296
NOSIP nitric oxide synthase interacting protein 2.15194
CLEC4E C-type lectin domain family 4, member E 2.09119
PLA2G2D phospholipase A2, group IID 2.02006
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.00013

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -6.10035
OXA1L oxidase (cytochrome c) assembly 1-like -5.54276
CCNB2 cyclin B2 -5.22333
COG7 component of oligomeric golgi complex 7 -4.2644
TRIB3 tribbles pseudokinase 3 -4.26315
VAT1 vesicle amine transport 1 -4.04988
CHMP4B charged multivesicular body protein 4B -3.98631
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.88393
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.74172
DSG2 desmoglein 2 -3.7302
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.40285
RHEB Ras homolog enriched in brain -3.39842
PEG10 paternally expressed 10 -3.24326
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.14878
TCTN1 tectonic family member 1 -2.88435
FBXO7 F-box protein 7 -2.60173
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.53904
EIF5 eukaryotic translation initiation factor 5 -2.41349
ITGB1BP1 integrin beta 1 binding protein 1 -2.40515
FAM193B family with sequence similarity 193, member B -2.26829
TRIM24 tripartite motif containing 24 -2.12711
CRABP2 cellular retinoic acid binding protein 2 -2.09697
MTCH1 mitochondrial carrier 1 -2.04108
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.00843
NMRK1 nicotinamide riboside kinase 1 -2.00524