| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iodoform 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN010_HEPG2_24H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 6.63657 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 6.21467 |
| CSK | c-src tyrosine kinase | 3.88958 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.7711 |
| MAMLD1 | mastermind-like domain containing 1 | 3.57642 |
| STAP2 | signal transducing adaptor family member 2 | 3.52275 |
| CBR3 | carbonyl reductase 3 | 3.4884 |
| MAP7 | microtubule-associated protein 7 | 3.20461 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.16625 |
| DENND2D | DENN/MADD domain containing 2D | 3.16294 |
| FZD7 | frizzled class receptor 7 | 3.15174 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.99606 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.95952 |
| LOC122526780 | uncharacterized LOC122526780 | 2.75759 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.74976 |
| DIPK1A | divergent protein kinase domain 1A | 2.68236 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.63368 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.6186 |
| LCN2 | lipocalin 2 | 2.5906 |
| FPGS | folylpolyglutamate synthase | 2.57356 |
| UBQLN2 | ubiquilin 2 | 2.56746 |
| ZFP36 | ZFP36 ring finger protein | 2.44488 |
| ABHD6 | abhydrolase domain containing 6 | 2.44191 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.35515 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.30082 |
| JADE2 | jade family PHD finger 2 | 2.2031 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.01388 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.01326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -7.32896 |
| GNAS | GNAS complex locus | -4.96313 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.43561 |
| RNF167 | ring finger protein 167 | -4.10123 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.96599 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.81102 |
| TLR4 | toll-like receptor 4 | -3.76859 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.73195 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.39115 |
| TCERG1 | transcription elongation regulator 1 | -3.26252 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.24531 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.16886 |
| COG2 | component of oligomeric golgi complex 2 | -3.15383 |
| NUP85 | nucleoporin 85kDa | -3.01822 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.86006 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.76782 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.6253 |
| ADI1 | acireductone dioxygenase 1 | -2.52216 |
| PCNA | proliferating cell nuclear antigen | -2.48596 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.34717 |
| LRRC17 | leucine rich repeat containing 17 | -2.32418 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.23332 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.21277 |
| TES | testin LIM domain protein | -2.0787 |
| GALE | UDP-galactose-4-epimerase | -2.01249 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -2.00655 |
