CRCGN010_HEPG2_24H:M22 Gene Set
Genes
55 genes differentially expressed following the CRCGN010_HEPG2_24H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
10.0
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
5.1515
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.99284
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.93025
|
|
CSK
|
c-src tyrosine kinase
|
4.65357
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.5233
|
|
SATB1
|
SATB homeobox 1
|
4.51631
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.10657
|
|
EVL
|
Enah/Vasp-like
|
3.92734
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
3.87201
|
|
BLMH
|
bleomycin hydrolase
|
3.82192
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.69044
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.56941
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.55979
|
|
CDC45
|
cell division cycle 45
|
3.52801
|
|
MAP7
|
microtubule-associated protein 7
|
3.42691
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.40788
|
|
PRKCQ
|
protein kinase C, theta
|
3.32124
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.74285
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.61172
|
|
SNRNP35
|
small nuclear ribonucleoprotein 35kDa (U11/U12)
|
2.47109
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.15249
|
|
DDTL
|
D-dopachrome tautomerase-like
|
2.10771
|
|
CENPO
|
centromere protein O
|
2.10108
|
|
CCNF
|
cyclin F
|
2.09583
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.04106
|
|
SKA1
|
spindle and kinetochore associated complex subunit 1
|
2.01567
|
|
TBP
|
TATA box binding protein
|
2.01552
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.67468
|
|
CDC20
|
cell division cycle 20
|
-9.00878
|
|
LDHD
|
lactate dehydrogenase D
|
-5.5291
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-5.31561
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-4.90111
|
|
VAT1
|
vesicle amine transport 1
|
-4.61446
|
|
GOLT1B
|
golgi transport 1B
|
-4.58411
|
|
RPN1
|
ribophorin I
|
-4.56552
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.48349
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.45434
|
|
SNX6
|
sorting nexin 6
|
-4.21908
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.20515
|
|
DNM1L
|
dynamin 1-like
|
-4.1317
|
|
DSG2
|
desmoglein 2
|
-4.10142
|
|
THAP11
|
THAP domain containing 11
|
-4.08691
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.02872
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.99752
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.78789
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.58003
|
|
RAI14
|
retinoic acid induced 14
|
-3.47882
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.80765
|
|
GNAS
|
GNAS complex locus
|
-2.56802
|
|
USP6NL
|
USP6 N-terminal like
|
-2.56319
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.16523
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.11286
|
|
FANCF
|
Fanconi anemia, complementation group F
|
-2.05695
|
|
BMAL2
|
basic helix-loop-helix ARNT like 2
|
-2.02087
|
