| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iodoform 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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54 genes differentially expressed following the CRCGN010_HEPG2_24H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 7.66551 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 5.56049 |
| CHN1 | chimerin 1 | 5.40173 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 5.01491 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.75386 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.55611 |
| ZNF589 | zinc finger protein 589 | 4.52588 |
| SFTPB | surfactant protein B | 3.77561 |
| CCNF | cyclin F | 3.40878 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.2552 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.99608 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.93788 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.91487 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.81043 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.6203 |
| PLSCR3 | phospholipid scramblase 3 | 2.61585 |
| CYCS | cytochrome c, somatic | 2.4924 |
| MOK | MOK protein kinase | 2.45823 |
| MNMIP1 | manchette microtubule inner protein 1 | 2.42049 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.40722 |
| MAP7 | microtubule-associated protein 7 | 2.30353 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.20256 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.1948 |
| TRIM2 | tripartite motif containing 2 | 2.15085 |
| MELK | maternal embryonic leucine zipper kinase | 2.0809 |
| COL3A1 | collagen, type III, alpha 1 | 2.03673 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.02655 |
| CHMP6 | charged multivesicular body protein 6 | 2.00074 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.95596 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -5.28522 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.20394 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -5.02719 |
| CCNB2 | cyclin B2 | -4.97902 |
| THAP11 | THAP domain containing 11 | -4.86008 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -4.47721 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.30646 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.97559 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.86763 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.51204 |
| TLCD3A | TLC domain containing 3A | -2.47499 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.43826 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.43446 |
| CCNB1 | cyclin B1 | -2.41797 |
| FAIM | Fas apoptotic inhibitory molecule | -2.39552 |
| USP6NL | USP6 N-terminal like | -2.37516 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.35085 |
| CDC25B | cell division cycle 25B | -2.27735 |
| RNF167 | ring finger protein 167 | -2.2564 |
| ICAM3 | intercellular adhesion molecule 3 | -2.24845 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.21592 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.19277 |
| HSPB1 | heat shock 27kDa protein 1 | -2.12195 |
| TRIB3 | tribbles pseudokinase 3 | -2.10885 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.01147 |