CRCGN010_HEPG2_24H:N01 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.21554
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
4.89084
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.87066
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.77622
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.65539
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.54835
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.47979
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.49535
|
|
GATA3
|
GATA binding protein 3
|
3.30714
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.96314
|
|
MEST
|
mesoderm specific transcript
|
2.86332
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.77429
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.62999
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.57104
|
|
STIMATE
|
STIM activating enhancer
|
2.53577
|
|
HSPA8
|
heat shock 70kDa protein 8
|
2.50688
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.49558
|
|
CHEK2
|
checkpoint kinase 2
|
2.48475
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.43513
|
|
SFTPB
|
surfactant protein B
|
2.33133
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.18296
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.12074
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-6.67893
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.44917
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.87126
|
|
LDHD
|
lactate dehydrogenase D
|
-4.8445
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.8356
|
|
TLR4
|
toll-like receptor 4
|
-4.33233
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.02205
|
|
PEG10
|
paternally expressed 10
|
-3.6367
|
|
SNX11
|
sorting nexin 11
|
-3.33586
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.22844
|
|
GNAS
|
GNAS complex locus
|
-3.01654
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.96328
|
|
ZNF586
|
zinc finger protein 586
|
-2.93155
|
|
CD58
|
CD58 molecule
|
-2.92644
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
-2.90664
|
|
GOLT1B
|
golgi transport 1B
|
-2.73605
|
|
SCAND1
|
SCAN domain containing 1
|
-2.62348
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.35151
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.32834
|
|
SPAG4
|
sperm associated antigen 4
|
-2.26522
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.2119
|
|
SLC22A4
|
solute carrier family 22 (organic cation/zwitterion transporter), member 4
|
-2.12816
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.07696
|
|
RNF167
|
ring finger protein 167
|
-2.0591
|
