CRCGN010_HEPG2_24H:N02 Gene Set
Genes
39 genes differentially expressed following the CRCGN010_HEPG2_24H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
6.21962
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.72116
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.37727
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
4.13929
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.84876
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.55129
|
|
GPATCH8
|
G patch domain containing 8
|
3.49381
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.81587
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.78447
|
|
GATA3
|
GATA binding protein 3
|
2.55141
|
|
CHN1
|
chimerin 1
|
2.41986
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.25957
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.25133
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.2508
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.24496
|
|
CYCS
|
cytochrome c, somatic
|
2.15385
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.10031
|
|
TEX10
|
testis expressed 10
|
2.09292
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.08933
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-8.12581
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-5.61005
|
|
CCNB2
|
cyclin B2
|
-5.49169
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.48818
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.23
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.73214
|
|
DNM1L
|
dynamin 1-like
|
-4.48723
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.99371
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.98314
|
|
PLK1
|
polo-like kinase 1
|
-3.6183
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.34558
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.28676
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.46968
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.27361
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.25964
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.21987
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.12076
|
|
RNF167
|
ring finger protein 167
|
-2.11382
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.11161
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.09286
|
