| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethylnitrosamine 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN010_HEPG2_24H:N05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 6.25152 |
| PRR15L | proline rich 15-like | 5.73492 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.08062 |
| MCOLN1 | mucolipin 1 | 4.44266 |
| E2F2 | E2F transcription factor 2 | 4.328 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.32573 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.09756 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.00105 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.96603 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.96202 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.92425 |
| MAMLD1 | mastermind-like domain containing 1 | 3.89373 |
| CHMP6 | charged multivesicular body protein 6 | 3.74126 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.67901 |
| EPHB2 | EPH receptor B2 | 3.61514 |
| LCN2 | lipocalin 2 | 3.54009 |
| MAP7 | microtubule-associated protein 7 | 3.3642 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 3.21454 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.89924 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 2.76057 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.49995 |
| CCNH | cyclin H | 2.39822 |
| MAD2L1BP | MAD2L1 binding protein | 2.2306 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 2.14103 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.1049 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 2.06736 |
| REG1A | regenerating islet-derived 1 alpha | 2.04597 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.01225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.06505 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.88036 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.53596 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.50918 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.43124 |
| NUP85 | nucleoporin 85kDa | -4.07182 |
| SLC35F2 | solute carrier family 35, member F2 | -3.96614 |
| UBE3C | ubiquitin protein ligase E3C | -3.85533 |
| GNAS | GNAS complex locus | -3.77208 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.67535 |
| ACOT9 | acyl-CoA thioesterase 9 | -3.56259 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.55509 |
| CHMP4B | charged multivesicular body protein 4B | -3.54485 |
| CDC20 | cell division cycle 20 | -3.4767 |
| VAT1 | vesicle amine transport 1 | -3.4108 |
| YME1L1 | YME1-like 1 ATPase | -3.18114 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.01912 |
| ZNF586 | zinc finger protein 586 | -2.92495 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.72114 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.6728 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.52313 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.35574 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.35337 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.3209 |
| SNX11 | sorting nexin 11 | -2.29384 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.24323 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.23714 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.20945 |
| CS | citrate synthase | -2.13109 |
| CDR2L | cerebellar degeneration-related protein 2-like | -2.12217 |
| PEG10 | paternally expressed 10 | -2.10585 |
| TLR4 | toll-like receptor 4 | -2.0684 |
