| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethylnitrosamine 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN010_HEPG2_24H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 6.81107 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.69687 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.55408 |
| KDM5A | lysine (K)-specific demethylase 5A | 4.35393 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.04112 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.98669 |
| CHN1 | chimerin 1 | 3.82573 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.59805 |
| UBQLN2 | ubiquilin 2 | 3.54704 |
| CSK | c-src tyrosine kinase | 3.52541 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.39653 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.39012 |
| STIMATE | STIM activating enhancer | 3.3828 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.33405 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.27246 |
| NOTCH1 | notch 1 | 3.27091 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.22642 |
| EVL | Enah/Vasp-like | 3.07205 |
| MSRA | methionine sulfoxide reductase A | 3.03544 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.02888 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.94249 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.86992 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.81243 |
| NOSIP | nitric oxide synthase interacting protein | 2.70621 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.68098 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.60488 |
| PRKCH | protein kinase C, eta | 2.60222 |
| MOK | MOK protein kinase | 2.51717 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.50215 |
| CCNF | cyclin F | 2.48139 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.42416 |
| GSK3B | glycogen synthase kinase 3 beta | 2.27476 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.22227 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.17509 |
| EDN1 | endothelin 1 | 2.16726 |
| TATDN2 | TatD DNase domain containing 2 | 2.15772 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 2.10457 |
| HEBP1 | heme binding protein 1 | 2.0577 |
| CYCS | cytochrome c, somatic | 2.05718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.75062 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.94101 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.65711 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.5093 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.39297 |
| TRIB3 | tribbles pseudokinase 3 | -4.01377 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.80023 |
| DSG2 | desmoglein 2 | -3.67909 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.60205 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.52738 |
| LDHD | lactate dehydrogenase D | -3.3285 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.24582 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.23209 |
| RNF167 | ring finger protein 167 | -3.11727 |
| PRPF4 | pre-mRNA processing factor 4 | -2.90196 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.62989 |
| THAP11 | THAP domain containing 11 | -2.58916 |
| CCNB1 | cyclin B1 | -2.48011 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.33905 |
| WASHC4 | WASH complex subunit 4 | -2.32194 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.31461 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.2792 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.24131 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.11085 |
| PEG10 | paternally expressed 10 | -2.03862 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.03397 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.01329 |
