| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | vinyl toluene 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN010_HEPG2_24H:N09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 8.09807 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.39029 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 5.18891 |
| CBR1 | carbonyl reductase 1 | 4.75504 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.64368 |
| E2F2 | E2F transcription factor 2 | 3.89766 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.83182 |
| HDGFL3 | HDGF like 3 | 3.82562 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.75267 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.46872 |
| SFTPB | surfactant protein B | 3.38909 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.29118 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.26233 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.05904 |
| NOSIP | nitric oxide synthase interacting protein | 2.9619 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 2.90018 |
| ABHD6 | abhydrolase domain containing 6 | 2.77222 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.72768 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.63634 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.52345 |
| HSPA1A | heat shock 70kDa protein 1A | 2.48467 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 2.39021 |
| MEST | mesoderm specific transcript | 2.35093 |
| JADE2 | jade family PHD finger 2 | 2.27753 |
| SORBS3 | sorbin and SH3 domain containing 3 | 2.26931 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.11864 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.11309 |
| IFT46 | intraflagellar transport 46 | 2.10492 |
| ZNF32 | zinc finger protein 32 | 2.104 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.06408 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -8.30264 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.24832 |
| CDC20 | cell division cycle 20 | -5.50782 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.8561 |
| VAT1 | vesicle amine transport 1 | -4.75309 |
| PCNA | proliferating cell nuclear antigen | -4.70918 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.53212 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.32956 |
| GOLT1B | golgi transport 1B | -4.18975 |
| CCDC86 | coiled-coil domain containing 86 | -3.99711 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.82885 |
| ACOT9 | acyl-CoA thioesterase 9 | -3.77521 |
| ENOPH1 | enolase-phosphatase 1 | -3.2479 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.22132 |
| HMG20B | high mobility group 20B | -3.16258 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.02788 |
| RBM15B | RNA binding motif protein 15B | -2.94629 |
| WASHC4 | WASH complex subunit 4 | -2.79223 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.54886 |
| MTA1 | metastasis associated 1 | -2.32574 |
| MEPCE | methylphosphate capping enzyme | -2.32169 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.21156 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -2.18428 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -2.17893 |
| TUBA3C | tubulin, alpha 3c | -2.15575 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.11406 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.06587 |
| TXNRD1 | thioredoxin reductase 1 | -2.02719 |
