| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | vinyl toluene 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN010_HEPG2_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 4.22491 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.87605 |
| KIF5C | kinesin family member 5C | 3.49052 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.25515 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.00357 |
| LCN2 | lipocalin 2 | 2.94652 |
| MOK | MOK protein kinase | 2.93072 |
| CSK | c-src tyrosine kinase | 2.90224 |
| NOTCH1 | notch 1 | 2.83756 |
| MAMLD1 | mastermind-like domain containing 1 | 2.83211 |
| VGLL4 | vestigial-like family member 4 | 2.73733 |
| GATA2 | GATA binding protein 2 | 2.70952 |
| COPS7A | COP9 signalosome subunit 7A | 2.40832 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.38335 |
| GPATCH8 | G patch domain containing 8 | 2.31037 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.29206 |
| UBQLN2 | ubiquilin 2 | 2.22378 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.17135 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 2.14491 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.12726 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 2.09305 |
| PLSCR3 | phospholipid scramblase 3 | 2.06535 |
| SORBS3 | sorbin and SH3 domain containing 3 | 2.05471 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) | 2.0354 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa | 2.02979 |
| EGF | epidermal growth factor | 2.01093 |
| GPN1 | GPN-loop GTPase 1 | 2.00685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -7.04099 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -5.15387 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.97049 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.8888 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.23325 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.82708 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.6927 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.57272 |
| CDC20 | cell division cycle 20 | -3.06579 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.88095 |
| TCTN1 | tectonic family member 1 | -2.81602 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.6767 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.62097 |
| ZNF586 | zinc finger protein 586 | -2.58307 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.45259 |
| SLC35F2 | solute carrier family 35, member F2 | -2.40481 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.40075 |
| PPOX | protoporphyrinogen oxidase | -2.24268 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.16249 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.14849 |
| PRMT7 | protein arginine methyltransferase 7 | -2.13668 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -2.11509 |
| RPS5 | ribosomal protein S5 | -2.03848 |
| PLA2G15 | phospholipase A2, group XV | -2.03473 |
| RHBDL1 | rhomboid, veinlet-like 1 (Drosophila) | -2.0307 |
