CRCGN010_HEPG2_24H:N11 Gene Set
Genes
50 genes differentially expressed following the CRCGN010_HEPG2_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.49609
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
5.06109
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
4.42176
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.27317
|
|
PRR15L
|
proline rich 15-like
|
4.24728
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
4.22134
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.00505
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.95992
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.91506
|
|
RRAGA
|
Ras-related GTP binding A
|
3.89287
|
|
CYCS
|
cytochrome c, somatic
|
3.74224
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.24706
|
|
NOTCH1
|
notch 1
|
3.21225
|
|
CCNA1
|
cyclin A1
|
3.17573
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.08003
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
2.79496
|
|
MAP7
|
microtubule-associated protein 7
|
2.54753
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.5417
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.47367
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.40793
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.33049
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.27841
|
|
MEST
|
mesoderm specific transcript
|
2.21349
|
|
SIX1
|
SIX homeobox 1
|
2.19965
|
|
HSPA8
|
heat shock 70kDa protein 8
|
2.18588
|
|
EVL
|
Enah/Vasp-like
|
2.13974
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.11569
|
|
HOMER1
|
homer scaffolding protein 1
|
2.0468
|
|
ACOT2
|
acyl-CoA thioesterase 2
|
2.00694
|
|
GPATCH8
|
G patch domain containing 8
|
2.00391
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-7.63363
|
|
TLR4
|
toll-like receptor 4
|
-5.61291
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.42903
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.34638
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.99774
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.98352
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.85049
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.66489
|
|
LDHD
|
lactate dehydrogenase D
|
-3.41935
|
|
CPNE3
|
copine III
|
-2.93528
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.70731
|
|
TSPAN4
|
tetraspanin 4
|
-2.69495
|
|
RAI14
|
retinoic acid induced 14
|
-2.55518
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.51984
|
|
SNX11
|
sorting nexin 11
|
-2.47878
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.38927
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.30291
|
|
GALC
|
galactosylceramidase
|
-2.1569
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.10579
|
|
USP6NL
|
USP6 N-terminal like
|
-2.0615
|
