| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cupferron 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN010_HEPG2_24H:N14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 6.45236 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.9253 |
| MAP7 | microtubule-associated protein 7 | 5.62089 |
| CCNF | cyclin F | 4.40198 |
| LPAR2 | lysophosphatidic acid receptor 2 | 4.37256 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.79117 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.649 |
| KLHL21 | kelch-like family member 21 | 3.59811 |
| TEX10 | testis expressed 10 | 3.55059 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.54577 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.54343 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.51056 |
| MEST | mesoderm specific transcript | 3.48116 |
| CHN1 | chimerin 1 | 3.45715 |
| KLHL9 | kelch-like family member 9 | 3.39596 |
| STK10 | serine/threonine kinase 10 | 3.38443 |
| CSK | c-src tyrosine kinase | 3.25166 |
| NOTCH1 | notch 1 | 3.18349 |
| ABHD6 | abhydrolase domain containing 6 | 3.10907 |
| GPATCH8 | G patch domain containing 8 | 3.07591 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.05671 |
| SQOR | sulfide quinone oxidoreductase | 3.0197 |
| MEF2C | myocyte enhancer factor 2C | 2.98651 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.94731 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.89894 |
| DENND2D | DENN/MADD domain containing 2D | 2.89666 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.84879 |
| EPHA3 | EPH receptor A3 | 2.52392 |
| MOK | MOK protein kinase | 2.40404 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.38772 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 2.36756 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.34733 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.23499 |
| HSPA8 | heat shock 70kDa protein 8 | 2.19365 |
| NOSIP | nitric oxide synthase interacting protein | 2.16522 |
| CCL21 | chemokine (C-C motif) ligand 21 | 2.0688 |
| CDC45 | cell division cycle 45 | 2.06641 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.06468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.8696 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.81159 |
| GNAS | GNAS complex locus | -4.60494 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.95555 |
| PLK1 | polo-like kinase 1 | -3.75779 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.72012 |
| SLC35F2 | solute carrier family 35, member F2 | -3.46313 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.41516 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.26738 |
| VAT1 | vesicle amine transport 1 | -3.264 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.18519 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -3.18271 |
| PEG10 | paternally expressed 10 | -3.14037 |
| YME1L1 | YME1-like 1 ATPase | -3.09078 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.05709 |
| CCNB2 | cyclin B2 | -2.79133 |
| ZNF586 | zinc finger protein 586 | -2.65253 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.64437 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.53053 |
| MYL9 | myosin, light chain 9, regulatory | -2.4986 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.42202 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.37545 |
| CD320 | CD320 molecule | -2.31841 |
| STAMBP | STAM binding protein | -2.18995 |
| TBCB | tubulin folding cofactor B | -2.18506 |
| VEGFB | vascular endothelial growth factor B | -2.12494 |
| GALE | UDP-galactose-4-epimerase | -2.09395 |
| THBS3 | thrombospondin 3 | -2.07346 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.07217 |
| MOCS3 | molybdenum cofactor synthesis 3 | -2.01294 |
| WDR7 | WD repeat domain 7 | -2.00966 |
