CRCGN010_HEPG2_24H:N16 Gene Set
Genes
43 genes differentially expressed following the CRCGN010_HEPG2_24H:N16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
6.10202
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.72003
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.293
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.73943
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.42621
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.30001
|
|
EPN2
|
epsin 2
|
4.09166
|
|
MAP7
|
microtubule-associated protein 7
|
4.0443
|
|
FZD7
|
frizzled class receptor 7
|
3.74626
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.68327
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.53018
|
|
LCN2
|
lipocalin 2
|
3.51047
|
|
STK10
|
serine/threonine kinase 10
|
3.48864
|
|
CHN1
|
chimerin 1
|
3.15747
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.042
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.89403
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.83342
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
2.56383
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.48837
|
|
SFTPB
|
surfactant protein B
|
2.26048
|
|
KIF5C
|
kinesin family member 5C
|
2.23127
|
|
GPATCH8
|
G patch domain containing 8
|
2.17054
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.11653
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.09588
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.30104
|
|
ZNF586
|
zinc finger protein 586
|
-4.99316
|
|
CD320
|
CD320 molecule
|
-4.86441
|
|
DSG2
|
desmoglein 2
|
-4.84333
|
|
CCNB2
|
cyclin B2
|
-4.81025
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.70764
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.27887
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.84596
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.49991
|
|
CCNB1
|
cyclin B1
|
-3.23866
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.18551
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.99076
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.93431
|
|
CD58
|
CD58 molecule
|
-2.55853
|
|
GNAS
|
GNAS complex locus
|
-2.55751
|
|
TRIB1
|
tribbles pseudokinase 1
|
-2.48039
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.30813
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.25283
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.15569
|
