CRCGN010_HEPG2_24H:N17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cupferron 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN010_HEPG2_24H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.8179
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.62863
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.48904
CXCL2 chemokine (C-X-C motif) ligand 2 4.30231
BZW2 basic leucine zipper and W2 domains 2 4.03603
CHN1 chimerin 1 3.83587
MAMLD1 mastermind-like domain containing 1 3.41818
NOSIP nitric oxide synthase interacting protein 3.32078
STK10 serine/threonine kinase 10 2.99821
CDPF1 cysteine-rich, DPF motif domain containing 1 2.98445
CHMP6 charged multivesicular body protein 6 2.9173
MTERF3 mitochondrial transcription termination factor 3 2.43422
CCNF cyclin F 2.23921
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.17961
PRKCH protein kinase C, eta 2.16041
LOC122526780 uncharacterized LOC122526780 2.11669
VAV3 vav 3 guanine nucleotide exchange factor 2.08544

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -7.26871
ZNF586 zinc finger protein 586 -6.08951
OXA1L oxidase (cytochrome c) assembly 1-like -6.02712
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.59283
CCNB2 cyclin B2 -4.51197
NT5DC2 5'-nucleotidase domain containing 2 -3.3823
CRELD2 cysteine-rich with EGF-like domains 2 -2.77828
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.74206
LOC124907782 dual specificity protein phosphatase 22 -2.73986
DSG2 desmoglein 2 -2.7359
LDHD lactate dehydrogenase D -2.45637
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.45087
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.41536
PECR peroxisomal trans-2-enoyl-CoA reductase -2.35032
PEG10 paternally expressed 10 -2.33925
WASHC4 WASH complex subunit 4 -2.28387
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.2078
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.14726
NGRN neugrin, neurite outgrowth associated -2.10108
PRPF4 pre-mRNA processing factor 4 -2.02102