CRCGN010_HEPG2_24H:N18 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.88323
|
|
MAP7
|
microtubule-associated protein 7
|
5.37614
|
|
RRAGA
|
Ras-related GTP binding A
|
4.08973
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.94752
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.89997
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.76749
|
|
CBR3
|
carbonyl reductase 3
|
3.75211
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.5726
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.51188
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.50911
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.03739
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.80628
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.53176
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.44802
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.40478
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.39281
|
|
HEBP1
|
heme binding protein 1
|
2.34777
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.34701
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.28199
|
|
NENF
|
neudesin neurotrophic factor
|
2.25123
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.17869
|
|
PRR15L
|
proline rich 15-like
|
2.17664
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.09958
|
|
LCN2
|
lipocalin 2
|
2.07586
|
|
HBA1
|
hemoglobin, alpha 1
|
2.02883
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.72726
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-6.52766
|
|
TLR4
|
toll-like receptor 4
|
-5.32254
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.78789
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.70935
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.62515
|
|
DNM1L
|
dynamin 1-like
|
-3.6167
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.15964
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.91316
|
|
LDHD
|
lactate dehydrogenase D
|
-2.88939
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.73049
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.71838
|
|
CCNB2
|
cyclin B2
|
-2.61817
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.56786
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.56632
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.53055
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.5064
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.50183
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.46083
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.44605
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.32871
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.11062
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.09286
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.03706
|
