| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 5,7-dichloro-4-(4-fluorophenoxy)quinoline 5.35 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN010_HEPG2_24H:N21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.14395 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.97059 |
| CHMP6 | charged multivesicular body protein 6 | 4.70928 |
| NOTCH1 | notch 1 | 4.69822 |
| LCN2 | lipocalin 2 | 4.62384 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.41501 |
| NMU | neuromedin U | 4.33346 |
| CYCS | cytochrome c, somatic | 4.03151 |
| EAPP | E2F-associated phosphoprotein | 3.86238 |
| CHN1 | chimerin 1 | 3.7154 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.45612 |
| SLC75A1 | solute carrier family 75 member 1 | 3.27606 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.22072 |
| UFM1 | ubiquitin-fold modifier 1 | 3.12033 |
| HSPA8 | heat shock 70kDa protein 8 | 3.07045 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.01658 |
| IDE | insulin-degrading enzyme | 2.90893 |
| MYLK | myosin light chain kinase | 2.82253 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.70673 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.62246 |
| PLSCR3 | phospholipid scramblase 3 | 2.6187 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.51048 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.40993 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.38682 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.27953 |
| CRYZ | crystallin, zeta (quinone reductase) | 2.21694 |
| SQOR | sulfide quinone oxidoreductase | 2.19893 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 2.13213 |
| KIFBP | kinesin family binding protein | 2.07924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -6.71453 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -6.68581 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.59299 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.41626 |
| LDHD | lactate dehydrogenase D | -4.83139 |
| TSPAN4 | tetraspanin 4 | -4.5638 |
| CDC20 | cell division cycle 20 | -4.51822 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.12879 |
| TCTN1 | tectonic family member 1 | -4.11292 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -4.02392 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.74513 |
| BLCAP | bladder cancer associated protein | -3.40644 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.27543 |
| PEG10 | paternally expressed 10 | -3.22795 |
| KIF14 | kinesin family member 14 | -2.60539 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.57872 |
| RPL39L | ribosomal protein L39-like | -2.57556 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.55162 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.49418 |
| TLR4 | toll-like receptor 4 | -2.4396 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.37928 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.33222 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.33075 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.33066 |
| SNX11 | sorting nexin 11 | -2.17815 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.10991 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.10551 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.04847 |
| MAGEA8 | melanoma antigen family A8 | -2.01443 |
