CRCGN010_HEPG2_24H:N23 Gene Set
Genes
51 genes differentially expressed following the CRCGN010_HEPG2_24H:N23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
7.50131
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.68113
|
|
NOTCH1
|
notch 1
|
4.36041
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.21297
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.19176
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.95203
|
|
MYLK
|
myosin light chain kinase
|
3.89098
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.85407
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.4472
|
|
GATA3
|
GATA binding protein 3
|
3.25956
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.15345
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.10107
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.92447
|
|
MEST
|
mesoderm specific transcript
|
2.87684
|
|
PRR15L
|
proline rich 15-like
|
2.7662
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.52811
|
|
LCN2
|
lipocalin 2
|
2.48275
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.44379
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.37258
|
|
TMPRSS3
|
transmembrane protease, serine 3
|
2.36041
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.31946
|
|
NUCB2
|
nucleobindin 2
|
2.23079
|
|
CA12
|
carbonic anhydrase XII
|
2.10608
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.08718
|
|
ARHGAP8
|
Rho GTPase activating protein 8
|
2.01968
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-6.13077
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.36342
|
|
TLR4
|
toll-like receptor 4
|
-5.36037
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.80714
|
|
ENOPH1
|
enolase-phosphatase 1
|
-4.45329
|
|
CCNB2
|
cyclin B2
|
-4.36175
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.14625
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.02528
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.84206
|
|
TCTN1
|
tectonic family member 1
|
-3.63437
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.31883
|
|
MGAT4B
|
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
|
-3.09515
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.01326
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.77168
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.56803
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.5376
|
|
SV2A
|
synaptic vesicle glycoprotein 2A
|
-2.5372
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.40384
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.37477
|
|
ODAM
|
odontogenic, ameloblast asssociated
|
-2.32983
|
|
CYFIP1
|
cytoplasmic FMR1 interacting protein 1
|
-2.30695
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.28703
|
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1
|
-2.24398
|
|
TNFRSF11B
|
tumor necrosis factor receptor superfamily, member 11b
|
-2.15949
|
|
CSPG4
|
chondroitin sulfate proteoglycan 4
|
-2.15122
|
|
ACVR1
|
activin A receptor, type I
|
-2.01048
|
