CRCGN010_HEPG2_24H:N24 Gene Set
Genes
43 genes differentially expressed following the CRCGN010_HEPG2_24H:N24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
8.26143
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.74817
|
|
STIMATE
|
STIM activating enhancer
|
6.31569
|
|
CYCS
|
cytochrome c, somatic
|
5.45593
|
|
MYLK
|
myosin light chain kinase
|
4.97542
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.9689
|
|
CSK
|
c-src tyrosine kinase
|
4.52508
|
|
UBQLN2
|
ubiquilin 2
|
4.51886
|
|
GPATCH8
|
G patch domain containing 8
|
3.81717
|
|
SLC35A3
|
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
|
3.80773
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.72713
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
3.68813
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.49282
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.29618
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.28988
|
|
CHN1
|
chimerin 1
|
3.27628
|
|
GTF2A2
|
general transcription factor IIA, 2, 12kDa
|
2.79714
|
|
ZNF589
|
zinc finger protein 589
|
2.72774
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.68365
|
|
SMIM41
|
small integral membrane protein 41
|
2.36158
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.31876
|
|
CISD1
|
CDGSH iron sulfur domain 1
|
2.29123
|
|
H2BC12
|
H2B clustered histone 12
|
2.1534
|
|
SFTPB
|
surfactant protein B
|
2.08194
|
|
PIK3C2A
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
|
2.0646
|
|
EDC3
|
enhancer of mRNA decapping 3
|
2.05745
|
|
RRAGA
|
Ras-related GTP binding A
|
2.03463
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-8.39197
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.60941
|
|
TUBB6
|
tubulin, beta 6 class V
|
-5.04758
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.90984
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-4.45018
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.84836
|
|
CAB39
|
calcium binding protein 39
|
-3.69629
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.3956
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-3.33799
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.18992
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-3.08933
|
|
USP6NL
|
USP6 N-terminal like
|
-2.92663
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.52558
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.21105
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.08832
|
|
HBG1
|
hemoglobin, gamma A
|
-2.02379
|
