CRCGN010_HEPG2_24H:O13 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:O13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.44298
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.0095
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.88867
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.69103
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.59531
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.58739
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.33017
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.22383
|
|
HYOU1
|
hypoxia up-regulated 1
|
3.19985
|
|
CHN1
|
chimerin 1
|
3.03375
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.91697
|
|
SFTPB
|
surfactant protein B
|
2.8966
|
|
CTSL
|
cathepsin L
|
2.82035
|
|
CDC45
|
cell division cycle 45
|
2.74114
|
|
MEST
|
mesoderm specific transcript
|
2.71867
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.55363
|
|
EGF
|
epidermal growth factor
|
2.54499
|
|
GPATCH8
|
G patch domain containing 8
|
2.47358
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.43206
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.26658
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.12387
|
|
TMEM176B
|
transmembrane protein 176B
|
2.07975
|
|
CSNK2B
|
casein kinase 2, beta polypeptide
|
2.04943
|
|
ORMDL2
|
ORMDL sphingolipid biosynthesis regulator 2
|
2.04119
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.01531
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.9443
|
|
CCNB2
|
cyclin B2
|
-5.92787
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.71471
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.0257
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.8216
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.57451
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.5047
|
|
LDHD
|
lactate dehydrogenase D
|
-3.50388
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.49768
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.14998
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.05562
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.01467
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.64129
|
|
PCMT1
|
protein-L-isoaspartate (D-aspartate) O-methyltransferase
|
-2.57062
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.39159
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.25942
|
|
WNT5B
|
wingless-type MMTV integration site family, member 5B
|
-2.23217
|
|
GNAS
|
GNAS complex locus
|
-2.2096
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.13888
|
|
TNFAIP8
|
tumor necrosis factor, alpha-induced protein 8
|
-2.04318
|
|
SLC9A1
|
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
|
-2.03026
|
