CRCGN010_HEPG2_24H:O14 Gene Set
Genes
50 genes differentially expressed following the CRCGN010_HEPG2_24H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
6.9987
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.25949
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.04393
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.89112
|
|
MYLK
|
myosin light chain kinase
|
4.44391
|
|
PRR15L
|
proline rich 15-like
|
4.31937
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.98331
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.94815
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.86858
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.45785
|
|
PRKCH
|
protein kinase C, eta
|
3.39014
|
|
HSPA8
|
heat shock 70kDa protein 8
|
3.3543
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
3.22986
|
|
CHEK2
|
checkpoint kinase 2
|
2.98224
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.9785
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.96195
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.57241
|
|
HOOK2
|
hook microtubule-tethering protein 2
|
2.55664
|
|
MAP7
|
microtubule-associated protein 7
|
2.51576
|
|
CYCS
|
cytochrome c, somatic
|
2.49266
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.37793
|
|
EPCAM
|
epithelial cell adhesion molecule
|
2.26187
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.14683
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.0691
|
|
PLOD3
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
|
2.04461
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.03308
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.8738
|
|
LDHD
|
lactate dehydrogenase D
|
-4.58421
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.56548
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.50475
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-4.43805
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.20357
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.96822
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.84851
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.81301
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.58786
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.44871
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.37815
|
|
ZNF586
|
zinc finger protein 586
|
-3.22667
|
|
GNAS
|
GNAS complex locus
|
-2.89816
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.80644
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.61043
|
|
PYCR1
|
pyrroline-5-carboxylate reductase 1
|
-2.32743
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.32023
|
|
ABHD18
|
abhydrolase domain containing 18
|
-2.29037
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.21103
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.18116
|
|
SLC28A1
|
solute carrier family 28 (concentrative nucleoside transporter), member 1
|
-2.0734
|
|
TMPRSS5
|
transmembrane protease, serine 5
|
-2.03511
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.01511
|
