| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fd & c yellow no. 6 10.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN010_HEPG2_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 4.27889 |
| LCN2 | lipocalin 2 | 4.27303 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.96555 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.76752 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.42285 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.15006 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.1443 |
| CCNH | cyclin H | 3.06326 |
| ATP11B | ATPase, class VI, type 11B | 2.97819 |
| CHMP6 | charged multivesicular body protein 6 | 2.9377 |
| NUP133 | nucleoporin 133kDa | 2.93008 |
| PRR15L | proline rich 15-like | 2.78637 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.75175 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.7013 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.65053 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.62668 |
| STIMATE | STIM activating enhancer | 2.62569 |
| E2F2 | E2F transcription factor 2 | 2.60802 |
| LOC122526780 | uncharacterized LOC122526780 | 2.57268 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.4987 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.49363 |
| FZD1 | frizzled class receptor 1 | 2.48609 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.32509 |
| EGF | epidermal growth factor | 2.31779 |
| CYCS | cytochrome c, somatic | 2.311 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.19529 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.18623 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.17311 |
| SFTPB | surfactant protein B | 2.14725 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.13786 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.12568 |
| COPS7A | COP9 signalosome subunit 7A | 2.11063 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.10967 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 2.04038 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.02454 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 2.01348 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -5.43578 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.1012 |
| FAIM | Fas apoptotic inhibitory molecule | -4.75135 |
| DNM1L | dynamin 1-like | -4.51391 |
| NUP85 | nucleoporin 85kDa | -3.99159 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.97371 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.64272 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.61378 |
| TRIB3 | tribbles pseudokinase 3 | -3.34558 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.32549 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.22225 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.19627 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.0546 |
| TLR4 | toll-like receptor 4 | -2.98931 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.93932 |
| PCNA | proliferating cell nuclear antigen | -2.92907 |
| DCK | deoxycytidine kinase | -2.78965 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.78206 |
| GNAS | GNAS complex locus | -2.77905 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.72074 |
| SAP30BP | SAP30 binding protein | -2.64069 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -2.52534 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.52202 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.5208 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.48906 |
| TES | testin LIM domain protein | -2.37225 |
| RBM34 | RNA binding motif protein 34 | -2.33617 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.30198 |
| RPS5 | ribosomal protein S5 | -2.17561 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.15291 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.13879 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.13661 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.03662 |
| TXNDC9 | thioredoxin domain containing 9 | -2.00114 |
