| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fd & c yellow no. 6 5.02 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN010_HEPG2_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C2CD2 | C2 calcium-dependent domain containing 2 | 8.87453 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.9716 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.88289 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.61998 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.29263 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.26159 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.16713 |
| SFTPB | surfactant protein B | 4.0846 |
| MAP7 | microtubule-associated protein 7 | 4.03298 |
| ATP11B | ATPase, class VI, type 11B | 4.02048 |
| CSK | c-src tyrosine kinase | 3.7571 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.73405 |
| TEX10 | testis expressed 10 | 3.70937 |
| NOTCH1 | notch 1 | 3.62324 |
| SMIM40 | small integral membrane protein 40 | 3.46007 |
| ZFP36 | ZFP36 ring finger protein | 3.3792 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.28925 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.23877 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.23748 |
| FZD7 | frizzled class receptor 7 | 3.23289 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.78797 |
| RPA3 | replication protein A3, 14kDa | 2.70236 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.68363 |
| KLHL9 | kelch-like family member 9 | 2.52219 |
| GPATCH8 | G patch domain containing 8 | 2.51646 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.44931 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.38526 |
| LCN2 | lipocalin 2 | 2.36715 |
| MMP1 | matrix metallopeptidase 1 | 2.18678 |
| HSPA1A | heat shock 70kDa protein 1A | 2.14226 |
| CISD1 | CDGSH iron sulfur domain 1 | 2.07854 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 | 2.00566 |
| CHN1 | chimerin 1 | 2.00483 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIB3 | tribbles pseudokinase 3 | -6.33151 |
| LDHD | lactate dehydrogenase D | -5.98573 |
| VDAC1 | voltage-dependent anion channel 1 | -5.63019 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.26548 |
| CCNB1 | cyclin B1 | -5.12384 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.05132 |
| ISOC1 | isochorismatase domain containing 1 | -5.00547 |
| CCNB2 | cyclin B2 | -4.8947 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.87121 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.69047 |
| HAT1 | histone acetyltransferase 1 | -4.62682 |
| PCNA | proliferating cell nuclear antigen | -3.97431 |
| TLCD3A | TLC domain containing 3A | -3.9399 |
| ZNF586 | zinc finger protein 586 | -3.83395 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.64683 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.56943 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.02635 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.86849 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.48663 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.36804 |
| MYL9 | myosin, light chain 9, regulatory | -2.34308 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.21855 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -2.11489 |
| TCTN1 | tectonic family member 1 | -2.10657 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.08696 |
| SNX6 | sorting nexin 6 | -2.07084 |
| CMC2 | C-x(9)-C motif containing 2 | -2.04491 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.02447 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | -2.00301 |
