CRCGN010_HEPG2_24H:O17 Gene Set
Genes
44 genes differentially expressed following the CRCGN010_HEPG2_24H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.12156
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.6654
|
|
CSK
|
c-src tyrosine kinase
|
4.66665
|
|
CHN1
|
chimerin 1
|
4.66212
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.49273
|
|
JADE2
|
jade family PHD finger 2
|
4.30278
|
|
STIMATE
|
STIM activating enhancer
|
4.04415
|
|
PRR15L
|
proline rich 15-like
|
3.17656
|
|
RRAGA
|
Ras-related GTP binding A
|
3.1217
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
3.11208
|
|
FZD7
|
frizzled class receptor 7
|
3.06921
|
|
IL1B
|
interleukin 1, beta
|
2.95144
|
|
STK10
|
serine/threonine kinase 10
|
2.85054
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.70966
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.63064
|
|
MMP1
|
matrix metallopeptidase 1
|
2.54437
|
|
VGLL4
|
vestigial-like family member 4
|
2.54323
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
2.54222
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.50307
|
|
MEST
|
mesoderm specific transcript
|
2.45463
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.41616
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.38536
|
|
SIRT3
|
sirtuin 3
|
2.38471
|
|
GATA2
|
GATA binding protein 2
|
2.36686
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.33725
|
|
SATB1
|
SATB homeobox 1
|
2.31631
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.23333
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.08841
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
2.02905
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-6.43841
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-5.39695
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.85334
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.75339
|
|
LDHD
|
lactate dehydrogenase D
|
-4.66642
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.86149
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.32137
|
|
THAP11
|
THAP domain containing 11
|
-2.83856
|
|
CCNB2
|
cyclin B2
|
-2.77419
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.5994
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.48709
|
|
PGM1
|
phosphoglucomutase 1
|
-2.31214
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.30784
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.28732
|
|
GDF15
|
growth differentiation factor 15
|
-2.1375
|
