CRCGN010_HEPG2_24H:O24 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:O24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CCNF
|
cyclin F
|
4.88746
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.19063
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.10947
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.95806
|
|
CBR3
|
carbonyl reductase 3
|
3.79261
|
|
CHN1
|
chimerin 1
|
3.70803
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
3.5356
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.48518
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.4587
|
|
DFFB
|
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
|
3.3299
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.06555
|
|
MEST
|
mesoderm specific transcript
|
2.85626
|
|
EPHA3
|
EPH receptor A3
|
2.85598
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.74769
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.70174
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.62136
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.54021
|
|
PRKCH
|
protein kinase C, eta
|
2.46781
|
|
PLS1
|
plastin 1
|
2.26421
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.2642
|
|
BAX
|
BCL2-associated X protein
|
2.195
|
|
MYLK
|
myosin light chain kinase
|
2.16473
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.07179
|
|
EGF
|
epidermal growth factor
|
2.03034
|
|
SNX7
|
sorting nexin 7
|
2.01963
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-4.80363
|
|
TCERG1
|
transcription elongation regulator 1
|
-4.4121
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.39379
|
|
VAT1
|
vesicle amine transport 1
|
-4.07759
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.75238
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.68656
|
|
CDC20
|
cell division cycle 20
|
-3.59707
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.4206
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.3832
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.29114
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.15118
|
|
ZNF586
|
zinc finger protein 586
|
-2.93793
|
|
TCTN1
|
tectonic family member 1
|
-2.88934
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.74544
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.63904
|
|
RBM34
|
RNA binding motif protein 34
|
-2.55377
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.43533
|
|
CCNB2
|
cyclin B2
|
-2.42548
|
|
XPO7
|
exportin 7
|
-2.40304
|
|
DNM1L
|
dynamin 1-like
|
-2.2049
|
|
GNAS
|
GNAS complex locus
|
-2.19924
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.18657
|
|
BLCAP
|
bladder cancer associated protein
|
-2.16004
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.13457
|
