CRCGN010_HEPG2_24H:P06 Gene Set
Genes
39 genes differentially expressed following the CRCGN010_HEPG2_24H:P06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RPL39L
|
ribosomal protein L39-like
|
4.5884
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.41799
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.36285
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.2167
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.64785
|
|
MAP7
|
microtubule-associated protein 7
|
3.57403
|
|
LCN2
|
lipocalin 2
|
3.50546
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.37303
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.19371
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.01659
|
|
ZNF589
|
zinc finger protein 589
|
2.87728
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.3863
|
|
MYLK
|
myosin light chain kinase
|
2.35638
|
|
GPATCH8
|
G patch domain containing 8
|
2.17973
|
|
MRAS
|
muscle RAS oncogene homolog
|
2.16634
|
|
E2F2
|
E2F transcription factor 2
|
2.13736
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.11714
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.09182
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.06238
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-9.40005
|
|
LDHD
|
lactate dehydrogenase D
|
-6.4795
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.76377
|
|
CCNB2
|
cyclin B2
|
-5.68994
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.67533
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.26697
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.12643
|
|
TLR4
|
toll-like receptor 4
|
-3.53524
|
|
CDC20
|
cell division cycle 20
|
-3.36676
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.32539
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.1375
|
|
CAB39
|
calcium binding protein 39
|
-3.09773
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.00335
|
|
RPS5
|
ribosomal protein S5
|
-2.74236
|
|
ZNF134
|
zinc finger protein 134
|
-2.48149
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.21341
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.17601
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.10418
|
|
SNX11
|
sorting nexin 11
|
-2.09377
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.0718
|
