CRCGN010_HEPG2_24H:P11 Gene Set
Genes
61 genes differentially expressed following the CRCGN010_HEPG2_24H:P11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.47754
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.78757
|
|
FZD7
|
frizzled class receptor 7
|
4.58332
|
|
PRR15L
|
proline rich 15-like
|
4.37181
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.95737
|
|
LCN2
|
lipocalin 2
|
3.9564
|
|
CHN1
|
chimerin 1
|
3.93223
|
|
E2F2
|
E2F transcription factor 2
|
3.87734
|
|
CCDC92
|
coiled-coil domain containing 92
|
3.83433
|
|
STIMATE
|
STIM activating enhancer
|
3.71224
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.60343
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.39431
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
3.39073
|
|
UBQLN2
|
ubiquilin 2
|
3.3691
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.13565
|
|
JADE2
|
jade family PHD finger 2
|
3.12487
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.93596
|
|
CCNA1
|
cyclin A1
|
2.69471
|
|
EPHA3
|
EPH receptor A3
|
2.57443
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.54683
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.48897
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.47733
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.44772
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.39017
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.35211
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.29692
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.27857
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.26629
|
|
STK10
|
serine/threonine kinase 10
|
2.21902
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.10104
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-6.24335
|
|
LDHD
|
lactate dehydrogenase D
|
-6.14443
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.81737
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.41489
|
|
GNAS
|
GNAS complex locus
|
-4.23363
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.89571
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.86114
|
|
TRAP1
|
TNF receptor-associated protein 1
|
-3.85651
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.65478
|
|
PEG10
|
paternally expressed 10
|
-3.64591
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-3.58592
|
|
DSG2
|
desmoglein 2
|
-3.41853
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.40108
|
|
ZNF586
|
zinc finger protein 586
|
-3.33754
|
|
CTSD
|
cathepsin D
|
-3.29232
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.21148
|
|
DCK
|
deoxycytidine kinase
|
-2.95144
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.87716
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.79147
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.7518
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.73239
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.72868
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.63337
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.52533
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.32564
|
|
HMG20B
|
high mobility group 20B
|
-2.28245
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.27667
|
|
SNX11
|
sorting nexin 11
|
-2.24517
|
|
STX4
|
syntaxin 4
|
-2.19858
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.19772
|
|
CAB39
|
calcium binding protein 39
|
-2.1732
|
