| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-methylene-bis(2-chloro?aniline) 1.21 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN010_HEPG2_24H:P12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.98089 |
| UBQLN2 | ubiquilin 2 | 3.7513 |
| NUCB2 | nucleobindin 2 | 3.73665 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.6896 |
| CHEK2 | checkpoint kinase 2 | 3.51546 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.23148 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 3.1686 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.11229 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.01139 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.89694 |
| CHMP6 | charged multivesicular body protein 6 | 2.82593 |
| CDC45 | cell division cycle 45 | 2.78471 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.7114 |
| NOSIP | nitric oxide synthase interacting protein | 2.68202 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.61605 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.53774 |
| MEF2C | myocyte enhancer factor 2C | 2.47376 |
| CTSL | cathepsin L | 2.41167 |
| PRKCH | protein kinase C, eta | 2.27975 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.26705 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.22875 |
| PLS1 | plastin 1 | 2.2274 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 2.17637 |
| MOK | MOK protein kinase | 2.17473 |
| STIMATE | STIM activating enhancer | 2.16474 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.16428 |
| MAP7 | microtubule-associated protein 7 | 2.16219 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.1436 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 2.13085 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.12845 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.09681 |
| HOXA10 | homeobox A10 | 2.07056 |
| CCDC15 | coiled-coil domain containing 15 | 2.0676 |
| KDM4D | lysine (K)-specific demethylase 4D | 2.05243 |
| DENND2D | DENN/MADD domain containing 2D | 2.0392 |
| S100A4 | S100 calcium binding protein A4 | 2.02439 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.1721 |
| CCNB2 | cyclin B2 | -5.89418 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.12751 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.39219 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.97109 |
| RSU1 | Ras suppressor protein 1 | -3.69618 |
| TLR4 | toll-like receptor 4 | -3.56545 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.35263 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.34478 |
| TUBB6 | tubulin, beta 6 class V | -3.32263 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.19486 |
| GDF15 | growth differentiation factor 15 | -2.8541 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.83852 |
| GOLT1B | golgi transport 1B | -2.8044 |
| VDAC1 | voltage-dependent anion channel 1 | -2.61277 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.57145 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.50168 |
| LDHD | lactate dehydrogenase D | -2.48906 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.41852 |
| COG2 | component of oligomeric golgi complex 2 | -2.39034 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.33236 |
| RNF167 | ring finger protein 167 | -2.25732 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.24502 |
| PEG10 | paternally expressed 10 | -2.14441 |
| CHMP4B | charged multivesicular body protein 4B | -2.09471 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.07718 |
| ZNF787 | zinc finger protein 787 | -2.06783 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.03149 |
