CRCGN010_HEPG2_24H:P16 Gene Set
Genes
56 genes differentially expressed following the CRCGN010_HEPG2_24H:P16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
10.0
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
6.90857
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
5.466
|
|
CSK
|
c-src tyrosine kinase
|
5.0
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.98825
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.9468
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.74985
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.74395
|
|
NOTCH1
|
notch 1
|
4.709
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.40455
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.20555
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.1877
|
|
CDC45
|
cell division cycle 45
|
3.2926
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.23812
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
3.11225
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.9437
|
|
CHN1
|
chimerin 1
|
2.8467
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
2.60047
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.59405
|
|
CYCS
|
cytochrome c, somatic
|
2.51215
|
|
GPATCH8
|
G patch domain containing 8
|
2.49353
|
|
SFTPB
|
surfactant protein B
|
2.40632
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.3744
|
|
CCNA1
|
cyclin A1
|
2.36035
|
|
CCRL2
|
chemokine (C-C motif) receptor-like 2
|
2.28235
|
|
KANK3
|
KN motif and ankyrin repeat domains 3
|
2.2379
|
|
SLC10A3
|
solute carrier family 10, member 3
|
2.21515
|
|
LONRF3
|
LON peptidase N-terminal domain and ring finger 3
|
2.1796
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
2.16315
|
|
LPL
|
lipoprotein lipase
|
2.15695
|
|
CHEK2
|
checkpoint kinase 2
|
2.0053
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-5.74315
|
|
CDC20
|
cell division cycle 20
|
-4.8391
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.78345
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.66275
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.34445
|
|
WASHC4
|
WASH complex subunit 4
|
-4.30822
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-4.07732
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.8561
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.56813
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.44403
|
|
MTA1
|
metastasis associated 1
|
-3.13032
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.11775
|
|
CAB39
|
calcium binding protein 39
|
-2.6737
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.466
|
|
FBXO7
|
F-box protein 7
|
-2.43075
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.36645
|
|
TP53RK
|
TP53 regulating kinase
|
-2.36575
|
|
RPS5
|
ribosomal protein S5
|
-2.3194
|
|
TCL1A
|
T-cell leukemia/lymphoma 1A
|
-2.14475
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.1121
|
|
SNRPE
|
small nuclear ribonucleoprotein polypeptide E
|
-2.1111
|
|
RAB3B
|
RAB3B, member RAS oncogene family
|
-2.08187
|
|
ATP5MJ
|
ATP synthase membrane subunit j
|
-2.0727
|
|
MRPL23
|
mitochondrial ribosomal protein L23
|
-2.00195
|
