CRCGN010_HEPG2_24H:P18 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
7.49797
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.75288
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.36467
|
|
LCN2
|
lipocalin 2
|
4.27021
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.01722
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.80084
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.59989
|
|
AXIN1
|
axin 1
|
3.31792
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.12906
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.07932
|
|
MCM3
|
minichromosome maintenance complex component 3
|
3.06737
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.83304
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.71567
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.6684
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.46235
|
|
CCNA1
|
cyclin A1
|
2.40825
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.32065
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.24845
|
|
KLHL9
|
kelch-like family member 9
|
2.19436
|
|
PRR15L
|
proline rich 15-like
|
2.18231
|
|
STAP2
|
signal transducing adaptor family member 2
|
2.13304
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.0835
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
2.06075
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.03155
|
|
XRCC6
|
X-ray repair complementing defective repair in Chinese hamster cells 6
|
2.02596
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.28941
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.43488
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.14272
|
|
RNF167
|
ring finger protein 167
|
-4.02072
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.95749
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.44623
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.30525
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.1157
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.88813
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.75448
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.72653
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.70464
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.67124
|
|
CDC20
|
cell division cycle 20
|
-2.65976
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.65768
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.62221
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.50723
|
|
NUP85
|
nucleoporin 85kDa
|
-2.35758
|
|
SNX11
|
sorting nexin 11
|
-2.3016
|
|
GNAS
|
GNAS complex locus
|
-2.20073
|
|
MRPL58
|
mitochondrial ribosomal protein L58
|
-2.06623
|
