| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzoic acid, sodium 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN010_HEPG2_24H:P20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 7.53897 |
| UBQLN2 | ubiquilin 2 | 7.41832 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 5.40488 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.42845 |
| GPATCH8 | G patch domain containing 8 | 4.31914 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.95778 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.85314 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.59993 |
| STIMATE | STIM activating enhancer | 3.54882 |
| LAGE3 | L antigen family, member 3 | 3.48631 |
| MYLK | myosin light chain kinase | 3.45777 |
| CTSL | cathepsin L | 3.27688 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.97567 |
| PRKCH | protein kinase C, eta | 2.90168 |
| E2F2 | E2F transcription factor 2 | 2.81569 |
| MCOLN1 | mucolipin 1 | 2.80696 |
| MEST | mesoderm specific transcript | 2.60072 |
| CYCS | cytochrome c, somatic | 2.48028 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.40367 |
| MAP7 | microtubule-associated protein 7 | 2.3899 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 2.34162 |
| ZNF589 | zinc finger protein 589 | 2.32349 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 2.28779 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.27443 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.15693 |
| LY6E | lymphocyte antigen 6 complex, locus E | 2.14134 |
| COQ3 | coenzyme Q3 methyltransferase | 2.1357 |
| RRAGA | Ras-related GTP binding A | 2.0709 |
| RAB21 | RAB21, member RAS oncogene family | 2.01923 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -5.25363 |
| TLR4 | toll-like receptor 4 | -5.07874 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.73447 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.96134 |
| LDHD | lactate dehydrogenase D | -3.67318 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.65021 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.61212 |
| CCDC86 | coiled-coil domain containing 86 | -3.57655 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.472 |
| HMG20B | high mobility group 20B | -3.43432 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.41647 |
| TP53BP2 | tumor protein p53 binding protein 2 | -3.39139 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.35531 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.35453 |
| VAT1 | vesicle amine transport 1 | -3.21114 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.00347 |
| SLC35F2 | solute carrier family 35, member F2 | -2.99037 |
| RNF167 | ring finger protein 167 | -2.81429 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.53642 |
| PLA2G15 | phospholipase A2, group XV | -2.53594 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.46562 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.45154 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.27497 |
| FAM111A | family with sequence similarity 111, member A | -2.22327 |
| BZW2 | basic leucine zipper and W2 domains 2 | -2.1371 |
| TCTN1 | tectonic family member 1 | -2.04809 |
| CDC25B | cell division cycle 25B | -2.03474 |
