| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzoic acid, sodium 10.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN010_HEPG2_24H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 7.19695 |
| MAP7 | microtubule-associated protein 7 | 5.84063 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.35434 |
| STK10 | serine/threonine kinase 10 | 4.30689 |
| EVL | Enah/Vasp-like | 4.26351 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.20459 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.02754 |
| NOTCH1 | notch 1 | 3.96474 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.81266 |
| MCOLN1 | mucolipin 1 | 3.80121 |
| EPN2 | epsin 2 | 3.79655 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.78144 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.57505 |
| E2F2 | E2F transcription factor 2 | 3.52463 |
| MYLK | myosin light chain kinase | 3.40702 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.12006 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.11535 |
| ZFP36 | ZFP36 ring finger protein | 2.92113 |
| IPO13 | importin 13 | 2.5633 |
| NUP85 | nucleoporin 85kDa | 2.54681 |
| JADE2 | jade family PHD finger 2 | 2.54335 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.5407 |
| MEST | mesoderm specific transcript | 2.4833 |
| CCNH | cyclin H | 2.39594 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.31746 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.27369 |
| ADIPOR1 | adiponectin receptor 1 | 2.1886 |
| GPATCH8 | G patch domain containing 8 | 2.18535 |
| SFTPB | surfactant protein B | 2.14452 |
| ELAC2 | elaC ribonuclease Z 2 | 2.14328 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 2.09775 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 2.08977 |
| PTK2 | protein tyrosine kinase 2 | 2.07594 |
| SSR1 | signal sequence receptor, alpha | 2.05382 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.04441 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.04221 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.0122 |
| MRC1 | mannose receptor, C type 1 | 2.00316 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIB3 | tribbles pseudokinase 3 | -8.20885 |
| PCNA | proliferating cell nuclear antigen | -6.2112 |
| ZNF586 | zinc finger protein 586 | -4.79256 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.27925 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.0788 |
| COG2 | component of oligomeric golgi complex 2 | -4.0762 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.97539 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.94945 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.87755 |
| LDHD | lactate dehydrogenase D | -3.79029 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.77962 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.74963 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.48422 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -3.44202 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.38838 |
| PDZD2 | PDZ domain containing 2 | -3.31509 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.11404 |
| GNAS | GNAS complex locus | -2.8886 |
| SCAND1 | SCAN domain containing 1 | -2.70492 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.46658 |
| TCTN1 | tectonic family member 1 | -2.4593 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.36526 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.29609 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.19897 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.14727 |
| TUBA4A | tubulin, alpha 4a | -2.13448 |
| FAM32A | family with sequence similarity 32, member A | -2.12859 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -2.06232 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.03638 |
| CAB39 | calcium binding protein 39 | -2.02774 |
| NCOA6 | nuclear receptor coactivator 6 | -2.01109 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -2.00933 |
