| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzoic acid, sodium 5.03 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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51 genes differentially expressed following the CRCGN010_HEPG2_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 5.48535 |
| CHN1 | chimerin 1 | 4.24295 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.0493 |
| MYLK | myosin light chain kinase | 3.85448 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.14895 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.0507 |
| DIPK1A | divergent protein kinase domain 1A | 2.9993 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.90564 |
| E2F2 | E2F transcription factor 2 | 2.89718 |
| ADRB2 | adrenoceptor beta 2, surface | 2.77541 |
| MSRA | methionine sulfoxide reductase A | 2.73479 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.68748 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.67731 |
| MAP7 | microtubule-associated protein 7 | 2.61657 |
| HOXA10 | homeobox A10 | 2.60915 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.57656 |
| CHMP6 | charged multivesicular body protein 6 | 2.47192 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.39517 |
| H2BC12 | H2B clustered histone 12 | 2.24935 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.22361 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.16216 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 2.15749 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.11967 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.10777 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 2.07932 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 2.02294 |
| EDN1 | endothelin 1 | 2.00633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -6.04755 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.99748 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.91344 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -5.18994 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.31588 |
| LDHD | lactate dehydrogenase D | -3.79103 |
| DNM1L | dynamin 1-like | -3.50328 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.10016 |
| TRIB3 | tribbles pseudokinase 3 | -3.00081 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.91312 |
| DSG2 | desmoglein 2 | -2.80303 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.63701 |
| CAB39 | calcium binding protein 39 | -2.5841 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -2.55433 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.53031 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.5076 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.49197 |
| CHMP4B | charged multivesicular body protein 4B | -2.47766 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.42588 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.30585 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.20889 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.16007 |
| CASC3 | cancer susceptibility candidate 3 | -2.13446 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.06029 |
